5-(4-甲氧基苯基)噁唑合成路线 （共 17 条）
反应条件
potassium carbonate in methanol van Leusen oxazole synthesis; 4 h; Heating;
参考文献
Besselievre, Francois; Piguel, Sandrine; Mahuteau-Betzer, Florence; Grierson, David S.
Organic Letters, 2008 , vol. 10, # 18 p. 4029 - 4032
反应条件
palladium diacetate; potassium carbonate; di-(1-adamantyl)-n-butylphosphine; 2,2,2-trimethylacetic acid in dimethylammonium 2,4-dichlorophenoxyacetate T=110°C; 16 h; Inert atmosphere; regioselective reaction;
参考文献
Strotman, Neil A.; Chobanian, Harry R.; Guo, Yan; He, Jiafang; Wilson, Jonathan E.
Organic Letters, 2010 , vol. 12, # 16 p. 3578 - 3581
反应条件
4-toluene-sulfonylmethyl isocyanide in acetonitrile T=70°C; 12 h;
参考文献
Barrett, Anthony G. M.; Cramp, Susan M.; Hennessy, Alan J.; Procopiou, Panayiotis A.; Roberts, Richard S.
Organic Letters, 2001 , vol. 3, # 2 p. 271 - 273
反应条件
tetrakis(triphenylphosphine) palladium(0); water; sodium carbonate in 1,4-dioxane T=80°C; Suzuki cross-coupling; Inert atmosphere;
参考文献
Primas, Nicolas; Bouillon, Alexandre; Lancelot, Jean-Charles; Rault, Sylvain
Tetrahedron, 2009 , vol. 65, # 32 p. 6348 - 6353
反应条件
tetra-n-butylammonium acetate; palladium diacetate in N,N-dimethyl acetamide T=70°C; 24 h; Inert atmosphere; regioselective reaction;
参考文献
Bellina, Fabio; Lessi, Marco; Manzini, Chiara
European Journal of Organic Chemistry, 2013 , # 25 p. 5621 - 5630
反应条件
tetrakis(triphenylphosphine) palladium(0); water; sodium carbonate in 1,4-dioxane T=80°C; Suzuki cross-coupling;
参考文献
Primas, Nicolas; Bouillon, Alexandre; Lancelot, Jean-Charles; Rault, Sylvain
Tetrahedron, 2009 , vol. 65, # 32 p. 6348 - 6353
反应条件
potassium carbonate in methanol T=55°C; 2 h; Cooling;
参考文献
Ding, Zhenhua; Yoshikai, Naohiko
Organic Letters, 2010 , vol. 12, # 18 p. 4180 - 4183
反应条件
potassium tert-butylate in tetrahydrofuran 2 h; Ambient temperature;
参考文献
Sasaki, Hideaki
Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 8 p. 1369 - 1371
反应条件
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); cesium fluoride in N,N-dimethyl-formamide T=80°C; Suzuki cross-coupling;
参考文献
Primas, Nicolas; Bouillon, Alexandre; Lancelot, Jean-Charles; Rault, Sylvain
Tetrahedron, 2009 , vol. 65, # 32 p. 6348 - 6353
反应条件
1: With boron tribromide in dichloromethane T=-78 - 20°C; 8 h; 2: With water; sodium hydrogencarbonate in methanol; diethyl ether; dichloromethane T=0°C;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2009/75960 A1, 2009 ;
Location in patent: Page/Page column 27 ;
WO 2009/075960 A1
