3-(4-氟-苯基)-1H-吲哚合成路线 （共 15 条）
反应条件
methanol; ammonium chloride; magnesium in tetrahydrofuran T=20°C; 2 h;
参考文献
Mesangeau, Christophe; Amata, Emanuele; Alsharif, Walid; Seminerio, Michael J.; Robson, Matthew J.; Matsumoto, Rae R.; Poupaert, Jacques H.; McCurdy, Christopher R.
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 10 p. 5154 - 5161
反应条件
2,6-di-tert-butyl-pyridine; copper(II) bis(trifluoromethanesulfonate) in dichloromethane T=35°C; 45 h;
参考文献
Phipps, Robert J.; Grimster, Neil P.; Gaunt, Matthew J.
Journal of the American Chemical Society, 2008 , vol. 130, # 26 p. 8172 - 8174
反应条件
potassium fluoride; 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; palladium diacetate in propionic acid T=20°C; 1 h;
参考文献
Angewandte Chemie, International Edition, , vol. 48, # 23 p. 4235 - 4238
反应条件
tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate in dimethyl sulfoxide T=40°C; 1.25 h;
参考文献
Synlett, , # 12 p. 1363 - 1366
反应条件
1,10-phenanthroline; palladium diacetate; trifluoroacetic acid in chlorobenzene T=100°C; 17 h;
参考文献
Chen, Yongxin; Guo, Shuaibo; Li, Kangning; Qu, Jinpeng; Yuan, Hua; Hua, Qiuru; Chen, Baohua
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 4 p. 711 - 715
反应条件
in quinoline; diethyl ether
参考文献
US5393761 A1, ;
US 5393761 A
反应条件
ruthenium dodecarbonyl; carbon monoxide; [Pd(Phen)2][BF4]; carbonic acid dimethyl ester in ethylene glycol dimethyl ether T=170°C; P=45004.5 Torr; 6 h; Inert atmosphere;
参考文献
Ragaini, Fabio; Ventriglia, Flavia; Hagar, Mohamed; Fantauzzi, Simone; Cenini, Sergio
European Journal of Organic Chemistry, 2009 , # 13 p. 2185 - 2189
反应条件
copper in various solvent(s) 120 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 26 p. 4823 - 4831
反应条件
1: 1.) conc. aq. HCl, NaNO2, 2.) aq. KOH / 1.) from 0 deg C to 5 deg C, 1.5 h, 2.) ethanol, RT, 2 h 2: conc. H2SO4 / methanol / 18 h / Heating 3: aq. NaOH / methanol / 1 h / Heating 4: copper / various solvent(s) / 120 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 26 p. 4823 - 4831
反应条件
1: aq. NaOH / methanol / 1 h / Heating 2: copper / various solvent(s) / 120 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 26 p. 4823 - 4831
