4-(1H-咪唑-1-基)苯甲酸甲酯合成路线 （共 8 条）
反应条件
potassium carbonate in dimethyl sulfoxide T=120°C; 3 h;
参考文献
Morgan, Thomas K.; Lis, Randall; Lumma, William C.; Nickisch, Klaus; Wohl, Ronald A.; et al.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 4 p. 1091 - 1097
反应条件
silica-supported ionic liquid in methanol T=50°C; 3 h;
参考文献
Liu, Ping; Li, Pinhua; Wang, Lei
Synthetic Communications, 2012 , vol. 42, # 17 p. 2595 - 2605
反应条件
cesium fluoride in N,N-dimethyl-formamide T=60°C; 20 h; Inert atmosphere;
参考文献
Dehe, Daniel; Munstein, Isabel; Reis, Andreas; Thiel, Werner R.
Journal of Organic Chemistry, 2011 , vol. 76, # 4 p. 1151 - 1154
反应条件
copper quinolate; tetra-(n-butyl)ammonium iodide in water; dimethyl sulfoxide T=120°C; 24 h;
参考文献
Zhu, Yan; Yan, Hong; Lu, Linhua; Liu, Defu; Rong, Guangwei; Mao, Jincheng
Journal of Organic Chemistry, 2013 , vol. 78, # 19 p. 9898 - 9905
反应条件
1.1: aq. methanol / 16 h / 20 °C 2.1: aq. NH4Cl / methanol / 1 h / Heating 2.2: aq. H3PO4 / methanol / Heating View Scheme
参考文献
Synthesis, , # 17 p. 2661 - 2666
反应条件
1: With ammonium chloride in methanol 1 h; Heating; 2: With phosphoric acid in methanol Heating;
参考文献
Synthesis, , # 17 p. 2661 - 2666
反应条件
lithium aluminium tetrahydride in tetrahydrofuran; water
参考文献
Merck and Co., Inc.
Patent: US5206240 A1, 1993 ;
US 5206240 A
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 10 p. 2883 - 2891
