1-叠氮基-2-{2-[2-(2-叠氮基乙氧基)乙氧基]乙氧基}乙烷合成路线 （共 13 条）
反应条件
1: With methanesulfonyl chloride; triethylamine in tetrahydrofuran 5 h; 2: With sodium azide; sodium hydrogencarbonate in water 24 h; Heating / reflux;
参考文献
WO2006/73314 A1, ;
Page/Page column 31 ;
反应条件
sodium azide in N,N-dimethyl-formamide T=80°C; 18 h;
参考文献
Chemical Communications, , vol. 48, # 45 p. 5650 - 5652
反应条件
sodium azide in N,N-dimethyl-formamide T=80°C; 40 h;
参考文献
WO2008/11157 A2, ;
Page/Page column 174 ;
反应条件
sodium azide in N,N-dimethyl-formamide T=60°C; 10 h;
参考文献
Journal of the American Chemical Society, , vol. 127, # 36 p. 12434 - 12435
反应条件
sodium azide in ethanol; N,N-dimethyl acetamide 6 h; Reflux;
参考文献
Tetrahedron, , vol. 65, # 36 p. 7385 - 7392
反应条件
1: With pyridine; p-toluenesulfonyl chloride in tetrahydrofuran T=20°C; 2.5 h; Inert atmosphere; 2: With sodium azide in ethanol 12 h; Reflux;
参考文献
Angewandte Chemie - International Edition, , vol. 51, # 9 p. 2151 - 2154
反应条件
hydrogen; palladium on barium sulfate in ethanol; water P=760 Torr; 30 h;
参考文献
Gunzenhauser; Biala; Strazewski
Nucleosides and Nucleotides, 1999 , vol. 18, # 6-7 p. 1223 - 1224
反应条件
hydrogenchloride; sodium chloride; citric acid in pyridine; ethanol
参考文献
Cetus Corporation
Patent: US4705886 A1, 1987 ;
反应条件
phosphoric acid; triphenylphosphine in diethyl ether; water 24 h; effect of dilution conditions; various reaction times; other reagent, solvent; Product distribution;
参考文献
Schwabacher, Alan W.; Lane, James W.; Schiesher, Matthew W.; Leigh, Krista M.; Johnson, Christopher W.
Journal of Organic Chemistry, 1998 , vol. 63, # 5 p. 1727 - 1729
反应条件
1: With hydrogenchloride in water T=0°C; Inert atmosphere; 2: With triphenylphosphine in diethyl ether T=0 - 20°C; 24 h; Inert atmosphere;
参考文献
Okoth, Ronald; Basu, Amit
Beilstein Journal of Organic Chemistry, 2013 , vol. 9, p. 608 - 612
