(R)-1-(4-氰基苯基)乙醇合成路线 （共 26 条）
反应条件
methanol; sodium tetrahydroborate in tetrahydrofuran T=0 - 20°C; 0.666667 h;
参考文献
MERCK SERONO S.A.; BOMBRUN, Agnes; QUATTROPANI, Anna; GONZALEZ, Jerome; DORBAIS, Jerome; KNIGHT, Chris; BAKER-GLENN, Charles
Patent: WO2012/4287 A1, 2012 ;
Location in patent: Page/Page column 116 ;
WO 2012/004287 A1
反应条件
NaH2PO2; 5 palladium on charcoal; tetrabutyl-ammonium chloride in 2-methyl tetrahydrofuran; water T=60°C; 18 h; Schlenk technique;
参考文献
Tetrahedron, , vol. 70, # 12 p. 2088 - 2095
反应条件
2-hydroxy-1,3-isoindolinedione; bromine; oxygen; Acridine Yellow G in acetonitrile T=75°C; P=2250.18 Torr; 5 h;
参考文献
Tetrahedron Letters, , vol. 47, # 11 p. 1763 - 1766
反应条件
anhydrous magnesium perchlorate in acetonitrile T=20°C; UV-irradiation; Further byproducts given;
参考文献
Journal of the American Chemical Society, , vol. 122, # 30 p. 7388 - 7389
反应条件
cesium fluoride in various solvent(s) T=60°C; 4 h;
参考文献
Tetrahedron Letters, , vol. 35, # 12 p. 1851 - 1854
反应条件
in diethyl ether T=-30°C; 2 h;
参考文献
Reetz, M. T.; Kyung, S. H.; Huellmann, M.
Tetrahedron, 1986 , vol. 42, # 11 p. 2931 - 2935
反应条件
ammonium hydroxide; titanium(III) chloride in methanol T=20 - 25°C; pH=10 - 11; 0.0833333 h;
参考文献
European Journal of Organic Chemistry, , # 19 p. 3326 - 3335
反应条件
water in water T=20 - 24°C; Equilibrium constant;
参考文献
Journal of the American Chemical Society, , vol. 106, # 5 p. 1361 - 1372
反应条件
perchloric acid; 10-methyl-9,10-dihydroacridine in acetonitrile-D3 T=61.9°C; 7 h; Title compound not separated from byproducts;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 62, # 9 p. 3049 - 3051
反应条件
Mortierella isabellina NRRL 1757
参考文献
Holland, Herbert L.; Carter, Ian M.; Chenchaiah, P. Chinna; Khan, Shaheer H.; Munoz, Benito; et al.
Tetrahedron Letters, 1985 , vol. 26, # 52 p. 6409 - 6412
