反应条件
1: hydrogenchloride / ethanol / |Reflux 2: 4-(N,N-dimethlyamino)pyridine; pyridine / dichloromethane / 1.33 h / -10 °C 3: N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide / 8 h / 70 °C View Scheme
参考文献
DECIPHERA PHARMACEUTICALS, LLC; FLYNN, Daniel L.; PETILLO, Peter A.; KAUFMAN, Michael D.
Patent: WO2013/36232 A2, 2013 ;
