tetrakis(triphenylphosphine) palladium(0); caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl in toluene T=100°C; 24 h;

1,3-dimethyl-1H-benzo[d]imidazol-3-ium iodide; sodium hydride in tetrahydrofuran 0.333333 h; Heating;

sodium hydride in N,N-dimethyl-formamide 0.0833333 h;

1: triethylamine / dichloromethane / 0 °C 2: ammonium hydroxide / isopropyl alcohol / 10 h / 90 °C / |Sealed tube 3: tetrakis(triphenylphosphine) palladium(0); caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl / toluene / 24 h / 100 °C View Scheme

1: ammonium hydroxide / isopropyl alcohol / 10 h / 90 °C / |Sealed tube 2: tetrakis(triphenylphosphine) palladium(0); caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl / toluene / 24 h / 100 °C View Scheme

sodium hydride in N,N-dimethyl-formamide 1 h;

ammonium acetate; ammonia T=165°C;