palladium 10 on activated carbon; hydrogen in methanol T=20°C; 18 h;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11343459', constants.ctx, '0')">disodium hydrogenphosphate</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '11380400', constants.ctx, '0')">sodium amalgam</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1098229', constants.ctx, '0')">methanol</a> <br />T=0&deg;C;&nbsp;3&nbsp;h;&nbsp;<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1.1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / -78 &deg;C / Inert atmosphere<br />1.2: -78 &deg;C<br />2.1: sodium amalgam; disodium hydrogenphosphate / methanol / 3 h / 0 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: trimethylaluminum / tetrahydrofuran; toluene<br />2: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 0.5 h / 0 &deg;C<br />3: sodium hydride / tetrahydrofuran / 1.5 h / 0 - 20 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: trimethylaluminum / tetrahydrofuran; toluene<br />2: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 0.5 h / 0 &deg;C<br />3: sodium hydride / tetrahydrofuran / 1.5 h / 0 - 20 &deg;C<br /> <br /> &nbsp;