1-苯乙基-2-吡咯烷酮合成路线 （共 10 条）
反应条件
tetrabutylammomium bromide; sodium hydroxide in dichloromethane; water T=100°C; 7 h;
参考文献
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM; ZHOU, Jia; CHEN, Haijun; JOHNSON, Kenneth; WANG, Cheng, Z.
Patent: WO2013/130501 A1, 2013 ;
Location in patent: Paragraph 076 ;
反应条件
sodium tetrahydroborate; RhH(CO)(triphenylphosphine)3 in dichloromethane; isopropyl alcohol T=100°C; P=26220 Torr; 24 h;
参考文献
Zhou, Jian-Qiang; Alper, Howard
Journal of Organic Chemistry, 1992 , vol. 57, # 12 p. 3328 - 3331
反应条件
disodium hydrogenphosphate; sodium amalgam in methanol T=0 - 20°C; Reduction; dehydrosulfinylation;
参考文献
Alonso, Diego A.; Alonso, Emma; Najera, Carmen; Ramon, Diego J.; Yus, Miguel
Tetrahedron, 1997 , vol. 53, # 13 p. 4835 - 4856
参考文献
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM; ZHOU, Jia; CHEN, Haijun; JOHNSON, Kenneth; WANG, Cheng, Z.
Patent: WO2013/130501 A1, 2013 ;
反应条件
1.1: N,N'-dimethylpropyleneurea; n-butyllithium / tetrahydrofuran; hexane / 0.08 h / -90 °C 1.2: 64 percent / tetrahydrofuran; hexane / -90 - 20 °C 2.1: 65 percent / Na2HPO4; sodium amalgam / methanol / 0 - 20 °C View Scheme
参考文献
Alonso, Diego A.; Alonso, Emma; Najera, Carmen; Ramon, Diego J.; Yus, Miguel
Tetrahedron, 1997 , vol. 53, # 13 p. 4835 - 4856
反应条件
1.1: N,N'-dimethylpropyleneurea; n-butyllithium / tetrahydrofuran; hexane / 0.08 h / -90 °C 1.2: 64 percent / tetrahydrofuran; hexane / -90 - 20 °C 2.1: 65 percent / Na2HPO4; sodium amalgam / methanol / 0 - 20 °C View Scheme
参考文献
Alonso, Diego A.; Alonso, Emma; Najera, Carmen; Ramon, Diego J.; Yus, Miguel
Tetrahedron, 1997 , vol. 53, # 13 p. 4835 - 4856
反应条件
sodium cyanoborohydride in formic acid 1.) rt, 3 h; 2.) 50 deg C, 2 h;
参考文献
Ainscow, R. Barry; Brettle, Roger; Shibib, Sa'ad M.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1781 - 1786
参考文献
Boekelheide; Godfrey
Journal of the American Chemical Society, 1953 , vol. 75, p. 3679,3682
反应条件
magnesium methanolate; acetic acid other reduction systems; Product distribution;
参考文献
Ainscow, R. Barry; Brettle, Roger; Shibib, Sa'ad M.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1781 - 1786
反应条件
1: phosphorus (V)-oxide; tetralin 2: palladium/charcoal; naphthalene; carbon dioxide View Scheme
参考文献
Boekelheide; Godfrey
Journal of the American Chemical Society, 1953 , vol. 75, p. 3679,3682
