(S)-3-羟基-1-苄基吡咯烷合成路线 （共 49 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 6 h; Reflux;
参考文献
MEDICHEM, S.A.
Patent: WO2009/153649 A1, 2009 ;
Location in patent: Page/Page column 10; 11 ;
反应条件
isopentyl nitrite in N,N-dimethyl-formamide T=65°C; 0.5 h;
参考文献
Aga, Mushtaq A.; Kumar, Brijesh; Rouf, Abdul; Shah, Bhahwal A.; Andotra, Samar S.; Taneja, Subhash C.
Helvetica Chimica Acta, 2013 , vol. 96, # 5 p. 969 - 977
反应条件
sodium carbonate in ethanol; water; ethyl acetate
参考文献
Samsung Fine Chemicals Co., Ltd.
Patent: US6566525 B1, 2003 ;
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 2 h; Reflux;
参考文献
Bonanni, Marco; Manuelli, Massimo; Goti, Andrea; Faggi, Cristina; Cardona, Francesca
Arkivoc, 2013 , vol. 2014, # 3 p. 54 - 64
反应条件
hydrogenchloride in water; 1,2-dichloro-ethane T=20 - 60°C; 3 h; Product distribution / selectivity;
参考文献
WO2009/11551 A2, ;
Page/Page column 13 ;
反应条件
triethylamine in tetrahydrofuran 4 h; Reflux;
参考文献
Pienaar, Daniel P.; Mitra, Robin K.; Deventer, Thomas I. van; Botes, Adriana L.
Tetrahedron Letters, 2008 , vol. 49, # 48 p. 6752 - 6755
反应条件
phosphoric acid in diethyl ether; water 3 h;
参考文献
Nagel, Ulrich; Nedden, Hans Guenter
Chemische Berichte, 1997 , vol. 130, # 3 p. 385 - 397
反应条件
1: 62 percent / ethanol / 165 - 170 °C 2: lithium aluminum hydride View Scheme
参考文献
Synthetic Communications, , vol. 15, # 7 p. 587 - 598
反应条件
lithium aluminium tetrahydride Yield given. Title compound not separated from byproducts;
参考文献
Synthetic Communications, , vol. 15, # 7 p. 587 - 598
