(S)-3-羟基-1-苄基吡咯烷合成路线 （共 49 条）
反应条件
potassium phosphate buffer; HXN-1100 cells T=30°C; 24 h; Yield givenYields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 10, # 7 p. 1323 - 1333
反应条件
1.1: water; sodium tetrahydroborate / methanol / 10 h / 20 °C 2.1: hypophosphorous ether; sodium azide; sulfuric acid; acetic acid / water / 39.5 h / 5 °C 2.2: pH 8 View Scheme
反应条件
1: 89 percent / KOH / ethanol / 12 h / Ambient temperature 2: HXN-1100 cells, aq. potassium phosphate buffer / 24 h / 30 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 10, # 7 p. 1323 - 1333
反应条件
Multistep reaction.;
参考文献
Morimoto, Masao; Sakai, Kenichi
Tetrahedron Asymmetry, 2008 , vol. 19, # 12 p. 1464 - 1468
反应条件
1.1: Reflux 1.2: Reflux 1.3: Reflux 2.1: ethanol; acetyl chloride / 20 °C 3.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 °C / Reflux View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 22, # 3 p. 257 - 263
参考文献
Tamazawa, Kazuharu; Arima, Hideki; Koijma, Tadao; Isomura, Yasuo; Okada, Minoru; et al.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 12 p. 2504 - 2511
反应条件
D-glucopyranose; oxygen T=30°C; pH=7.5; 2 h; aq. phosphate bufferEnzymatic reaction; enantioselective reaction;
参考文献
Chemical Communications, , vol. 48, # 38 p. 4618 - 4620
反应条件
sodium hydroxide; sodium acetate 1.) DMSO, 120 deg C, 50 min, 2.) MeOH, 25 deg C, 1 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Bioscience, Biotechnology and Biochemistry, , vol. 59, # 7 p. 1287 - 1290
反应条件
ferredoxin reductase; His-tagged ferredoxin; His-tagged P450pyr hydroxylase I83H/M305Q/A77S mutant; nicotinamide adenine dinucleotide; oxygen T=30°C; pH=7.5; 0.0833333 h; aq. phosphate bufferEnzymatic reaction; Kinetics; Reagent/catalystConcentration; optical yield given as percent eeenantioselective reaction;
参考文献
Chemical Communications, , vol. 48, # 38 p. 4618 - 4620
