1-叔丁氧碳基-3-吡咯烷酮合成路线

参考文献

ACHAOGEN, INC.; MAIANTI, Juan Pablo; AGGEN, James Bradley; DOZZO, Paola; GOLDBLUM, Adam Aaron; HILDEBRANDT, Darin James; KANE, Timothy Robert; GLIEDT, Micah James; LINSELL, Martin Sheringham; HANESSIAN, Stephen; GIGUERE, Alexandre
Patent: WO2011/44498 A1, 2011 ;
Location in patent: Page/Page column 64-65, 72 ;

101385-93-71-叔丁氧碳基-3-吡咯烷酮+

74-89-5甲胺

454712-26-61-Boc-3-甲氨基吡咯烷

参考文献

WO2009/76387 A1, ;

Page/Page column 42 ;
WO 2009/076387 A1

101385-93-71-叔丁氧碳基-3-吡咯烷酮

3760-52-93-吡咯烷酮盐酸盐

参考文献

Aebi, Johannes; Binggeli, Alfred; Green, Luke; Hartmann, Guido; Maerki, Hans P.; Mattei, Patrizio; Ricklin, Fabienne; Roche, Olivier
Patent: US2009/29963 A1, 2009 ;
Location in patent: Page/Page column 14 ;
US 20090029963 A1

917-64-6magnesium,carbanide,iodide+

101385-93-71-叔丁氧碳基-3-吡咯烷酮

921592-91-83-羟基-3-甲基吡咯烷盐酸盐

参考文献

Xuanzhu Pharma Co., Ltd.; ZHANG, Hui; FAN, Mingwei; SUN, Liang
Patent: EP2703398 A1, 2014 ;
Location in patent: Paragraph 0075; 0076; 0077 ;

1774-47-6三甲基碘化亚砜+

101385-93-71-叔丁氧碳基-3-吡咯烷酮

301226-25-51-氧杂-5-氮杂螺[2.4]庚烷-5-甲酸叔丁酯

参考文献

XI, Ning; WANG, Tingjin; YI, Lei
Patent: WO2013/138210 A1, 2013 ;
Location in patent: Paragraph 0209 ;

101385-93-71-叔丁氧碳基-3-吡咯烷酮

845894-03-31-Boc-3-氟-4-氧代吡咯烷

参考文献

Coleman, Paul J.; Cox, Christopher D.
Patent: US2006/287302 A1, 2006 ;
Location in patent: Page/Page column 35-36 ;

101385-93-71-叔丁氧碳基-3-吡咯烷酮

657428-42-74,6-二氢-1H-吡咯[3,4-C]吡唑-5-甲酸丁酯

参考文献

MERCK SHARP and DOHME CORP.; ARROYO, Itzia; KRUEGER, Davida; CHEN, Ping; MOMENT, Aaron; BIFTU, Tesfaye; SHEEN, Faye; ZHANG, Yanfeng; MERCK SHARPE and DOHME LTD.
Patent: WO2013/3249 A1, 2013 ;

1450-75-52′-羟基-5′-溴苯乙酮+

101385-93-71-叔丁氧碳基-3-吡咯烷酮

1291076-20-4

参考文献

DAC S.R.L.; VARASI, Mario; THALER, Florian; AMICI, Raffaella; ABATE, Agnese; FULCO, Maria Carmela; MINUCCI, Saverio; MERCURIO, Ciro
Patent: WO2011/45265 A2, 2011 ;
Location in patent: Page/Page column 26 ;
WO 2011/045265 A1

101385-93-71-叔丁氧碳基-3-吡咯烷酮

1395493-13-6

参考文献

MERCK SHARP and DOHME CORP.; HICKS, Jacqueline, D.; BIFTU, Tesfaye; CHEN, Ping; QIAN, Xiaoxia; WILKENING, Robert, R.
Patent: WO2011/146358 A1, 2011 ;

101385-93-71-叔丁氧碳基-3-吡咯烷酮

1289267-20-4

参考文献

Biftu, Tesfaye; Qian, Xiaoxia; Chen, Ping; Feng, Dennis; Scapin, Giovanna; Gao, Ying-Duo; Cox, Jason; Sinha Roy, Ranabir; Eiermann, George; He, Huabing; Lyons, Kathy; Salituro, Gino; Patel, Sangita; Petrov, Alexander; Xu, Feng; Xu, Shiyao Sherrie; Zhang, Bei; Caldwell, Charles; Wu, Joseph K.; Weber, Ann E.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 19 p. 5361 - 5366