1-叔丁氧碳基-3-吡咯烷酮合成路线

905274-03-52-(三氟甲基)-5H-吡咯并[3,4-d]嘧啶-6(7H)-羧酸叔丁酯

参考文献

Biftu, Tesfaye; Qian, Xiaoxia; Chen, Ping; Feng, Dennis; Scapin, Giovanna; Gao, Ying-Duo; Cox, Jason; Sinha Roy, Ranabir; Eiermann, George; He, Huabing; Lyons, Kathy; Salituro, Gino; Patel, Sangita; Petrov, Alexander; Xu, Feng; Xu, Shiyao Sherrie; Zhang, Bei; Caldwell, Charles; Wu, Joseph K.; Weber, Ann E.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 19 p. 5361 - 5366

24067-17-24-硝基苯基硼酸+

101385-93-71-叔丁氧碳基-3-吡咯烷酮

908334-28-13-(4-氨基苯基)吡咯烷-1-羧酸叔丁酯

参考文献

CANCER THERAPEUTICS CRC PTY LIMITED; HOLMES, Ian, Peter; BERGMAN, Ylva; LUNNISS, Gillian Elizabeth; NIKAC, Marica; CHOI, Neil; HEMLEY, Catherine Fae; WALKER, Scott Raymond; FOITZIK, Richard Charles; GANAME, Danny; LESSENE, Romina
Patent: WO2012/110773 A1, 2012 ;
Location in patent: Page/Page column 149; 150; 151 ;
WO 2012/110773 A1

37595-74-7N-苯基双(三氟甲烷磺酰)亚胺+

24067-17-24-硝基苯基硼酸+

101385-93-71-叔丁氧碳基-3-吡咯烷酮

908334-28-13-(4-氨基苯基)吡咯烷-1-羧酸叔丁酯

参考文献

CANCER THERAPEUTICS CRC PTY LTD; DEVLIN, Mark Graeme; STREET, Ian Philip; TONG, Warwick Bonner
Patent: WO2014/27199 A1, 2014 ;
Location in patent: Page/Page column 152-153 ;

101385-93-71-叔丁氧碳基-3-吡咯烷酮

908334-28-13-(4-氨基苯基)吡咯烷-1-羧酸叔丁酯

参考文献

AFRAXIS, INC.; CAMPBELL, David; DURÓN, Sergio, G.
Patent: WO2013/43232 A2, 2013 ;
WO 2013/043232 A2

31166-44-6苄基-1-哌嗪碳酸酯+

101385-93-71-叔丁氧碳基-3-吡咯烷酮

436852-08-34-(吡咯烷-3-基)哌嗪-1-羧酸苄酯

参考文献

NOVARTIS AG; NOVARTIS PHARMA GMBH
Patent: WO2007/121923 A1, 2007 ;
Location in patent: Page/Page column 95 ;
WO 2007/121923 A1

546-68-9钛酸四异丙酯+

31166-44-6苄基-1-哌嗪碳酸酯+

101385-93-71-叔丁氧碳基-3-吡咯烷酮

436852-08-34-(吡咯烷-3-基)哌嗪-1-羧酸苄酯

参考文献

Bilodeau, Mark T.; Hartman, George D.; Hoffman JR., Jacob M.; Sisko, John T.; Manley, Peter J.; Smith, Anthony M.; Tucker, Thomas J.; Lumma JR., William C.; Rodman, Leonard
Patent: US2002/137755 A1, 2002 ;
US 20020137755 A1

145100-51-22-[N,正双(三氟甲烷烷磺酰)氨基]-5-氯吡啶+

101385-93-71-叔丁氧碳基-3-吡咯烷酮

630121-86-73-(三氟甲基磺酰氧基)-2H-吡咯-1(5h)-羧酸叔丁酯

参考文献

Purandare, Ashok Vinayak; Wan, Honghe; Huynh, Tram N.
Patent: US2006/235037 A1, 2006 ;
Location in patent: Page/Page column 60 ;
US 20060235037 A1

37595-74-7N-苯基双(三氟甲烷磺酰)亚胺+

101385-93-71-叔丁氧碳基-3-吡咯烷酮

630121-86-73-(三氟甲基磺酰氧基)-2H-吡咯-1(5h)-羧酸叔丁酯

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG; BENTZIEN, Joerg, Martin; BOYER, Stephen, James; BURKE, Jennifer; ELDRUP, Anne, Bettina; GUO, Xin; HUBER, John, David; KIRRANE, Thomas, Martin; SOLEYMANZADEH, Fariba; SWINAMER, Alan, David
Patent: WO2010/5783 A1, 2010 ;
Location in patent: Page/Page column 151 ;
WO 2010/005783 A1

37595-74-7N-苯基双(三氟甲烷磺酰)亚胺+

101385-93-71-叔丁氧碳基-3-吡咯烷酮

参考文献

CANCER THERAPEUTICS CRC PTY LTD; DEVLIN, Mark Graeme; STREET, Ian Philip; TONG, Warwick Bonner
Patent: WO2014/27199 A1, 2014 ;
Location in patent: Page/Page column 152 ;

37595-74-7N-苯基双(三氟甲烷磺酰)亚胺+

101385-93-71-叔丁氧碳基-3-吡咯烷酮

630121-86-73-(三氟甲基磺酰氧基)-2H-吡咯-1(5h)-羧酸叔丁酯+

456-64-4三氟甲烷磺基苯胺

参考文献

SANOFI-AVENTIS
Patent: US2009/176775 A1, 2009 ;
Location in patent: Page/Page column 33-34 ;