反应条件
1: With lithium aluminium tetrahydride; AlCl3, aluminium chloride in tetrahydrofuran
T=0°C; 1 h;
2: 3-bromo-naphthalene-2-carboxylic acid ethyl ester in tetrahydrofuran
T=0°C; 1.5 h;
3: With ammonia in tetrahydrofuran; water
参考文献
Eisai RandD Management Co., Ltd.
Patent: EP2062901 A1, 2009 ;
Location in patent: Page/Page column 14-15 ;
