(S)-1-N-叔丁氧羰基-3-羟基吡咯烷合成路线 （共 24 条）
反应条件
triethylamine in 1,4-dioxane Inert atmosphere;
参考文献
Fransson, Rebecca; McCracken, Alison N.; Chen, Bin; McMonigle, Ryan J.; Edinger, Aimee L.; Hanessian, Stephen
ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 10 p. 969 - 973
反应条件
sodium hydrogencarbonate in water T=20°C; 65 h;
参考文献
Houghton, Peter G.; Humphrey, Guy R.; Kennedy, Derek J.; Roberts, D. Craig; Wright, Stanley H. B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 13 p. 1421 - 1424
反应条件
potassium carbonate in tetrahydrofuran; water
参考文献
Kaneka Corporation
Patent: EP1947083 A1, 2008 ;
Location in patent: Page/Page column 14 ;
反应条件
hydrogen; palladium hydroxide - carbon in methanol; water P=2068.59 Torr; 2 h;
参考文献
Merck Sharp and Dohme, Ltd.
Patent: US5854268 A1, 1998 ;
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran 4 h;
参考文献
WO2007/24113 A1, ;
Page/Page column 19-20 ;
反应条件
triethylamine in water
反应条件
Leifsonia sp. S749 cells alcohol dehydrogenase; β-NADP+; isopropyl alcohol in phosphate buffer T=25°C; pH=7.0; 24 h;
参考文献
Inoue, Kousuke; Makino, Yoshihide; Itoh, Nobuya
Tetrahedron Asymmetry, 2005 , vol. 16, # 15 p. 2539 - 2549
反应条件
ammonia in methanol T=0°C;
参考文献
Kocalka, Petr; Pohl, Radek; Rejman, Dominik; Rosenberg, Ivan
Tetrahedron, 2006 , vol. 62, # 24 p. 5763 - 5774
反应条件
1: dimethylformamide 2: NH3 / methanol View Scheme
参考文献
Nucleosides, Nucleotides and Nucleic Acids, , vol. 24, # 5-7 p. 805 - 808
反应条件
1: 85 percent / pyridine / CH2Cl2 / 20 °C 2: dimethylformamide / 72 h / 110 °C 3: 4.2 g / ammonia / methanol / 0 °C View Scheme
参考文献
Tetrahedron, , vol. 62, # 24 p. 5763 - 5774
