丙炔基4-甲氧基苯甲酸酯合成路线 （共 10 条）
反应条件
DBU; 5-hydro-3-oxaoctafluoropentanesulfonyl fluoride in dichloromethane T=20°C; 37 h;
参考文献
Yan, Zhaohua; Tian, Weisheng; Zeng, Fanrong; Dai, Yanfeng
Tetrahedron Letters, 2009 , vol. 50, # 23 p. 2727 - 2729
反应条件
triethylamine in dichloromethane T=20°C;
参考文献
Pereira, Guilherme R.; Brandao, Geraldo Celio; Arantes, Lucas M.; De Oliveira Jr., Haliton A.; De Paula, Renata Cristina; Do Nascimento, Maria Fernanda A.; Dos Santos, Fabio M.; Da Rocha, Ramon K.; Lopes, Julio Cesar D.; De Oliveira, Alaide Braga
European Journal of Medicinal Chemistry, 2014 , vol. 73, p. 295 - 309
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran; N,N-dimethyl-formamide T=60°C; 3 h; regioselective reaction;
参考文献
Kutsumura, Noriki; Kubokawa, Keisuke; Saito, Takao
Synthesis, 2011 , # 15 p. 2377 - 2382
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran; N,N-dimethyl-formamide T=60°C; 2 h; regioselective reaction;
参考文献
Kutsumura, Noriki; Kubokawa, Keisuke; Saito, Takao
Synthesis, 2011 , # 15 p. 2377 - 2382
反应条件
1,3,5-trimethylphenyl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate; Ru(bpz)3(PF6)2; 1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine in acetonitrile T=20°C;
参考文献
Zhao, Junfeng; Mueck-Lichtenfeld, Christian; Studer, Armido
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 6 p. 1098 - 1106
反应条件
1: With copper(l) iodide in chloroform T=20°C; 0.166667 h; 2: With 2,3-dicyano-5,6-dichloro-p-benzoquinone in chloroform 1 h; 3: With water in chloroform T=20°C; 12 h;
参考文献
Fu, Liang; Yao, Chang-Jiang; Chang, Ning-Jie; Chen, Jia-Rong; Lu, Liang-Qiu; Xiao, Wen-Jing
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 3 p. 506 - 508
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20°C;
参考文献
Zhang, Liying; Jia, Xiaojian; Dong, Jizhe; Chen, Dongyin; Liu, Jun; Zhang, Luyong; Wen, Xiaoan
Chemical Biology and Drug Design, 2014 , vol. 83, # 3 p. 297 - 305
反应条件
1.1: iodine / dichloromethane / 20 °C 2.1: copper(l) iodide / chloroform / 0.17 h / 20 °C 2.2: 1 h 2.3: 12 h / 20 °C View Scheme
参考文献
Fu, Liang; Yao, Chang-Jiang; Chang, Ning-Jie; Chen, Jia-Rong; Lu, Liang-Qiu; Xiao, Wen-Jing
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 3 p. 506 - 508
反应条件
boron tribromide in dichloromethane T=20°C; 0.25 h;
参考文献
Punna, Sreenivas; Meunier, Stephane; Finn
Organic Letters, 2004 , vol. 6, # 16 p. 2777 - 2779
反应条件
1: 88 percent / BBr3 / CH2Cl2 / 0.25 h / 20 °C
2: 68 percent / DMAP; DCC / CH2Cl2 / 10 h / 20 °C
3: 35 percent / BBr3 / CH2Cl2 / 2 h / 20 °C
View Scheme
参考文献
Punna, Sreenivas; Meunier, Stephane; Finn
Organic Letters, 2004 , vol. 6, # 16 p. 2777 - 2779
