3,6 - 二甲氧基哒嗪-4-硼酸合成路线 (共 1 条)
反应条件
1: With tri-isopropoxy-borane; diisopropylamine in tetrahydrofuran T=-70 - 3°C; 2: With water in tetrahydrofuran T=-20 - 24°C; 3: With hydrogen bromide in water pH=5 - 6; 2 h;
参考文献
ASTRAZENECA AB; ALHAMBRA, Cristobal; CHANG, Hui-Fang (Amy); CHAPDELAINE, Marc; HERZOG, Keith, John; SCHMIESING, Richard, J
Patent: WO2011/21979 A1, 2011 ;
Location in patent: Page/Page column 24 ;
WO 2011/021979 A1