1.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.25 h / -50 °C
1.2: 0.58 h / -50 - 20 °C
2.1: triethylamine; lithium chloride / acetonitrile / 18 h / 20 °C
3.1: hydrogen / palladium 10 on activated carbon / ethanol / 4 h / 65 °C / 2327.23 Torr
View Scheme
参考文献
Brotherton-Pleiss, Christine E.; Harris, III, Ralph New; Loe, Bradley E.; Lopez-Tapia, Francisco Javier; Rege, Pankaj D.; Repke, David Bruce; Stabler, Russell Stephen; Walker, Keith Adrian Murray
Patent: US2011/71143 A1, 2011 ;
