1: n-BuLi / tetrahydrofuran; hexane / 1.) 0 deg C, 30 min, 2.) r.t., 70 min 2: p-TsOH*H2O / methanol / 1 h / Ambient temperature 3: 99 percent / pyridine / 3.5 h / Ambient temperature 4: 73 percent / dichloromaleic anhydride / 200 °C 5: 99 percent / 2 M KOH / ethanol / 19 h / Heating 6: 72 percent / CBr4, PPh3 / CH2Cl2 / 6 h / Ambient temperature 7: n-BuLi / hexane; tetrahydrofuran; hexamethylphosphoric acid triamide / 1.) -78 deg C, 3.5 h, 2.) -78 deg C to r.t., 17 h 8: p-TsOH*H2O / methanol / 1 h / Heating 9: 68 percent / CBr4, PPh3 / diethyl ether; CH2Cl2 / 1.) 0 deg C, 1 h, 2.) r.t., 17 h 10: 1.) EtMgBr, 2.) CuCN / 1.) THF, reflux, 1 h; r.t., 15 min, 2.) 0 deg C, 30 min; r.t., 15 h 11: H2, quinoline / 5percent Pd/BaSO4 / pyridine / 1.92 h / 750.06 Torr / Ambient temperature 12: 63 percent / AlI3, (+)-limonene / CS2 / 1.) r.t., 10 min, 2.) reflux, 30 min View Scheme

1: 1) EtMgBr, CuI 2: TsOH / methanol; H2O 3: 89 percent / PCC View Scheme

mercuric triflate; water; N,N,N',N'-tetramethyl-urea in dichloromethane; acetonitrile T=20°C; 6 h;

1: 1) n-BuLi, 2) HMPT / 1) THF, hexane, 10 deg C, 2) <25 deg C, 0.5 h 2: 83 percent / AcOH 3: 97 percent / H2, quinoline / 5percent Pd/BaSO4 / methanol View Scheme

1: n-BuLi / tetrahydrofuran; hexane / 1.) 0 deg C, 30 min, 2.) r.t., 70 min 2: p-TsOH*H2O / methanol / 1 h / Ambient temperature 3: 99 percent / pyridine / 3.5 h / Ambient temperature 4: 73 percent / dichloromaleic anhydride / 200 °C 5: 99 percent / 2 M KOH / ethanol / 19 h / Heating 6: 72 percent / CBr4, PPh3 / CH2Cl2 / 6 h / Ambient temperature 7: 63 percent / n-BuLi / tetrahydrofuran; hexane; hexamethylphosphoric acid triamide 8: 97 percent / H2, quinoline / 5percent Pd/CaCO3 / cyclohexane / 750.06 Torr 9: 80 percent / AlI3, cyclohexene / CS2 / 0.17 h / Heating View Scheme

toluene-4-sulfonic acid

in dimethyl sulfoxide 1.) 0 deg C, 3 h, 2.) RT, 12 h;

暂无反应条件数据

tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; 48 h;

1: 75 percent / aq. HBr / 40 h / 80 °C 2: 100 percent / aq. HCl / 16 h / 20 °C 3: 72 percent / dimethylsulfoxide / 12 h / 10 °C View Scheme