N-苄基-2-氯-9-甲基-9H-嘌呤-6-胺合成路线 （共 8 条）
反应条件
sodium hydride in N,N-dimethyl-formamide T=20°C; 24 h;
参考文献
Oh, Chang-Hyun; Lee, Su-Chul; Lee, Ki-Soo; Woo, Eun-Rhan; Hong, Chang Yong; Yang, Boem-Seok; Baek, Dae Jin; Cho, Jung-Hyuck
Archiv der Pharmazie, 1999 , vol. 332, # 6 p. 187 - 190
反应条件
triethylamine in butan-1-ol T=120°C; 0.5 h; Inert atmosphereMicrowave irradiation;
参考文献
Liang, Mary; Tarr, Tyler B.; Bravo-Altamirano, Karla; Valdomir, Guillermo; Rensch, Gabriel; Swanson, Lauren; Destefino, Nicholas R.; Mazzarisi, Cara M.; Olszewski, Rachel A.; Wilson, Gabriela Mustata; Meriney, Stephen D.; Wipf, Peter
ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 12 p. 985 - 990
反应条件
1: 80.5 percent / butan-1-ol / 5 h / 100 °C 2: 90.5 percent / NaH / dimethylformamide / 24 h / 20 °C View Scheme
参考文献
Parker, Charles W.; Entsch, Barrie; Letham, David S.
Phytochemistry (Elsevier), 1986 , vol. 25, # 2 p. 303 - 310
反应条件
sodium hydride in N,N-dimethyl-formamide
参考文献
Schow, Steven R.; Mackman, Richard L.; Blum, Cheri L.; Brooks, Eric; Horsma, Amy G.; Joly, Alison; Kerwar, Suresh S.; Lee, Gavin; Shiffman, Dov; Nelson, Marek G.; Wang, Xingbo; Wick, Michael M.; Zhang, Xiaoming; Lum, Robert T.
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 21 p. 2697 - 2702
反应条件
1: butan-1-ol / Heating 2: NaH / dimethylformamide View Scheme
参考文献
Oh, Chang-Hyun; Lee, Su-Chul; Lee, Ki-Soo; Woo, Eun-Rhan; Hong, Chang Yong; Yang, Boem-Seok; Baek, Dae Jin; Cho, Jung-Hyuck
Archiv der Pharmazie, 1999 , vol. 332, # 6 p. 187 - 190
反应条件
1: 66.2 percent / aq. NaNO2, aq. HOAc / H2O / 2 h / 70 - 80 °C 2: 39.9 percent / POCl3, NEt3 / 3 h / Heating 3: 80.5 percent / butan-1-ol / 5 h / 100 °C 4: 90.5 percent / NaH / dimethylformamide / 24 h / 20 °C View Scheme
参考文献
Oh, Chang-Hyun; Lee, Su-Chul; Lee, Ki-Soo; Woo, Eun-Rhan; Hong, Chang Yong; Yang, Boem-Seok; Baek, Dae Jin; Cho, Jung-Hyuck
Archiv der Pharmazie, 1999 , vol. 332, # 6 p. 187 - 190
反应条件
1: 39.9 percent / POCl3, NEt3 / 3 h / Heating 2: 80.5 percent / butan-1-ol / 5 h / 100 °C 3: 90.5 percent / NaH / dimethylformamide / 24 h / 20 °C View Scheme
参考文献
Oh, Chang-Hyun; Lee, Su-Chul; Lee, Ki-Soo; Woo, Eun-Rhan; Hong, Chang Yong; Yang, Boem-Seok; Baek, Dae Jin; Cho, Jung-Hyuck
Archiv der Pharmazie, 1999 , vol. 332, # 6 p. 187 - 190
反应条件
in N,N-dimethyl-formamide T=160°C; 2.5 h;
参考文献
Hocart, Charles H.; Letham, David S.; Parker, Charles W.
Phytochemistry (Elsevier), 1991 , vol. 30, # 8 p. 2477 - 2486
