2-氯-3,4-二甲氧基吡啶盐酸盐合成路线 （共 15 条）
反应条件
1: 52 percent / NiCl2*6H2O/(C6H5)3P, Zn, KI / dimethylformamide / 12 h / 50 °C
2: 53 percent / 30percent H2O2, (CH3CO)2O, / 14 h / 100 °C
3: 77 percent / 33percent HBr/CH3COOH / 5 h / Heating
View Scheme
参考文献
Dehmlow, Eckehard, V.; Schulz, Hans-Joachim
Tetrahedron Letters, 1985 , vol. 26, # 40 p. 4903 - 4906
反应条件
triphenylphosphine; potassium iodide; nickel dichloride; zinc in N,N-dimethyl-formamide
T=50°C; 12 h;
参考文献
Dehmlow, Eckehard V.; Schulz, Hans-Joachim
Liebigs Annalen der Chemie, 1987 , p. 857 - 862
反应条件
in N,N-dimethyl-formamide
T=50°C; 4 h;
参考文献
Dehmlow, Eckehard, V.; Schulz, Hans-Joachim
Tetrahedron Letters, 1985 , vol. 26, # 40 p. 4903 - 4906
反应条件
1: 52 percent / NiCl2*6H2O/(C6H5)3P, Zn, KI / dimethylformamide / 12 h / 50 °C
2: 53 percent / 30percent H2O2, (CH3CO)2O, / 14 h / 100 °C
View Scheme
参考文献
Dehmlow, Eckehard, V.; Schulz, Hans-Joachim
Tetrahedron Letters, 1985 , vol. 26, # 40 p. 4903 - 4906
反应条件
1: 52 percent / NiCl2*6H2O/(C6H5)3P, Zn, KI / dimethylformamide / 12 h / 50 °C
2: 53 percent / 30percent H2O2, (CH3CO)2O, / 14 h / 100 °C
3: 77 percent / 33percent HBr/CH3COOH / 5 h / Heating
4: 336 h / Irradiation
View Scheme
参考文献
Dehmlow, Eckehard, V.; Schulz, Hans-Joachim
Tetrahedron Letters, 1985 , vol. 26, # 40 p. 4903 - 4906
