(5R)-5-甲基-2-(苯硫基)环己酮合成路线 （共 9 条）
反应条件
lithium diisopropyl amide in tetrahydrofuran T=-78 - 20°C;
参考文献
Haruta, Yoshinari; Onizuka, Kazumitsu; Watanabe, Kyouichi; Kono, Kyoko; Nohara, Akihiro; Kubota, Kenichi; Imoto, Shuhei; Sasaki, Shigeki
Tetrahedron, 2008 , vol. 64, # 30-31 p. 7211 - 7218
反应条件
1: 94 percent / 30percent H2O2; LiOH / methanol / 8 h / 25 °C 2: 84 percent / tetrahydrofuran / 18 h / Heating View Scheme
参考文献
Organic Letters, , vol. 4, # 21 p. 3571 - 3574
反应条件
sodium tert-pentoxide in various solvent(s) 5 h; Heating;
参考文献
Mutti, Stephane; Daubie, Christophe; Decalogne, Francois; Fournier, Robert; Rossi, Pierre
Tetrahedron Letters, 1996 , vol. 37, # 18 p. 3125 - 3128
反应条件
in tetrahydrofuran 18 h; Heating;
参考文献
Chen, Yuzhong; Evarts Jr., Jerry B.; Torres, Eduardo; Fuchs, Philip L.
Organic Letters, 2002 , vol. 4, # 21 p. 3571 - 3574
反应条件
ammonium chloride in water 1 h; Ambient temperature;
参考文献
Caine, Drury; Procter, Katherine; Cassell, Roger A.
Journal of Organic Chemistry, 1984 , vol. 49, # 14 p. 2647 - 2648
反应条件
1: 1)NaH / 1)THF, room temp., 0.5 h 2)reflux, 24 h 2: 0.75 g / NH4Cl / H2O / 1 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 49, # 14 p. 2647 - 2648
反应条件
1: 1)NaH / 1)THF, room temp., 0.5 h 2)reflux, 24 h 2: 0.75 g / NH4Cl / H2O / 1 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 49, # 14 p. 2647 - 2648
反应条件
1: MCPBA
2: 1) LDA / 1) THF, HMPA, -40 to -35 deg C, 2 h, 2) THF, HMPA, -40 to -35 deg C, 2 h
View Scheme
参考文献
Walts; Roush
Tetrahedron, 1985 , vol. 41, # 17 p. 3463 - 3478
反应条件
3-chloro-benzenecarboperoxoic acid in dichloromethane
T=-78°C;
参考文献
Avery; Chong; Jennings-White
Journal of the American Chemical Society, 1992 , vol. 114, # 3 p. 974 - 979
