6-(4-甲氧基苯基)-4,5-二氢-3(2H)-哒嗪酮合成路线 (共 9 条)
反应条件
hydrazine carboxylic acid ester T=90°C; 3 h; Green chemistry;
参考文献
Tetrahedron Letters, , vol. 54, # 11 p. 1384 - 1388
反应条件
1: With trifluoroacetic acid in dichloromethane 16 h; 2: With hydrazine hydrate in ethanol 2.5 h; Reflux;
参考文献
EP2168959 A1, ;
Page/Page column 156 ;
反应条件
sodium acetate; hydrazine hydrate in methanol condensation; Heating;
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 39, # 8 p. 614 - 619
反应条件
1: AlCl3 2: alkaline solution; hydrazine sulfate View Scheme
参考文献
Chemische Berichte, , vol. 34, p. 3263
反应条件
hydrazine hydrate in ethanol 2 h; Ambient temperatureor heating, 2h;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 21, p. 763 - 764
反应条件
1.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / 0 °C / |Inert atmosphere 1.2: 3 h / 0 - 20 °C / |Inert atmosphere 2.1: trifluoroacetic acid / dichloromethane / 16 h 3.1: hydrazine hydrate / ethanol / 2.5 h / |Reflux View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 1 p. 375 - 381
反应条件
hydrazine hydrate in ethanol
参考文献
Journal of Enzyme Inhibition and Medicinal Chemistry, , vol. 28, # 3 p. 552 - 559
反应条件
copper dichloride in acetonitrile 0.25 h; Heating;
参考文献
Csende; Szabo; Bernath; Stajer
Synthesis, 1995 , # 10 p. 1240 - 1242
反应条件
1: sodium hydroxide; m-nitrobenzene sulfonic acid sodium salt / water / 1.5 h / |Reflux
2: AlCl3, aluminium chloride / dichloromethane / 19 h / 20 °C
View Scheme
参考文献
Ochiai, Koji; Takita, Satoshi; Kojima, Akihiko; Eiraku, Tomohiko; Iwase, Kazuhiko; Kishi, Tetsuya; Ohinata, Akira; Yageta, Yuichi; Yasue, Tokutaro; Adams, David R.; Kohno, Yasushi
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 1 p. 375 - 381