5-亚硝基-6-(苯基甲氧基)-2,4-嘧啶二胺合成路线 （共 8 条）
反应条件
acetic acid; sodium nitrite in water T=80°C; 1 h;
参考文献
Cancer Research Campaign Technology Limited
Patent: US6677345 B1, 2004 ;
Location in patent: Page/Page column 11 ;
US 6677345 B1
反应条件
benzyl alcohol beim Erwaermen des Reaktionsprodukts mit NaNO2 und wss. Essigsaeure;
参考文献
Roth et al.
Journal of the American Chemical Society, 1951 , vol. 73, p. 2864,2867
反应条件
1: NaH / dimethylsulfoxide / 80 °C 2: NaNO2; aq. AcOH / 80 °C View Scheme
参考文献
Komatsu, Toru; Johnsson, Kai; Okuno, Hiroyuki; Bito, Haruhiko; Inoue, Takanari; Nagano, Tetsuo; Urano, Yasuteru
Journal of the American Chemical Society, 2011 , vol. 133, # 17 p. 6745 - 6751
反应条件
pyridine in dichloromethane T=0°C;
参考文献
Xu, Ming; De Giacomo, Fabio; Paterson, Duncan E.; George, Tesmol G.; Vasella, Andrea
Chemical Communications, 2003 , # 12 p. 1452 - 1453
反应条件
triethylamine in tetrahydrofuran T=20°C;
参考文献
Xu, Ming; De Giacomo, Fabio; Paterson, Duncan E.; George, Tesmol G.; Vasella, Andrea
Chemical Communications, 2003 , # 12 p. 1452 - 1453
反应条件
1: 73 percent / Et3N / tetrahydrofuran / 20 °C 2: 82 percent / PPh3 / o-xylene / 24 h / Heating View Scheme
参考文献
Xu, Ming; De Giacomo, Fabio; Paterson, Duncan E.; George, Tesmol G.; Vasella, Andrea
Chemical Communications, 2003 , # 12 p. 1452 - 1453
反应条件
lead(IV) acetate in acetic acid
12.5 h;
参考文献
Boyle, Peter H.; Lockhart, Ronan J.
Tetrahedron, 1984 , vol. 40, # 5 p. 879 - 886
反应条件
1: 79 percent / Et3N / tetrahydrofuran / 20 °C
2: 94 percent / PPh3 / o-xylene / 24 h / Heating
View Scheme
参考文献
Xu, Ming; De Giacomo, Fabio; Paterson, Duncan E.; George, Tesmol G.; Vasella, Andrea
Chemical Communications, 2003 , # 12 p. 1452 - 1453
