1: 85 percent / HCl / methanol / 15 h / 0 °C 2: 1.) MeLi, TMEDA; 2.) KOH / 1.) diethyl ether, 0 deg C, 10 min; 2.) methanol, 15 min 3: DMAP, 1,3-dicyclohexylcarbodiimide / CH2Cl2 / 0 °C 4: 96 percent / DMAP / pyridine / 3.33 h / 50 °C 5: 96 percent / KOH / methanol / 8.5 h / Ambient temperature 6: 1.) oxalyl chloride, DMSO; 2.) triethylamine / 1.) CH2Cl2, -60- -50 deg C, 15 min; 2.) -60- -50 deg C, 5 min 7: 45 percent / LiCl, DBU / dimethylsulfoxide / 39 h / Ambient temperature 8: 1.) triethylsilane; 2.) 48 percent aq. HF / 1.) (PPh3)3RhCl / 1.) benzene, 70 deg C, 40 min; 2.) CH3CN, rt. 50 min 9: 39 percent / NaBH4 / methanol / 0.75 h / Ambient temperature 10: 85 percent / p-Ts-OH*H2O / benzene / 0.67 h / Ambient temperature View Scheme