4-氯烟酸合成路线

参考文献

Chemische Berichte, , vol. 92, p. 2266,2270
Arkiv foer Kemi, , vol. 14, p. 419,422

Journal of Organic Chemistry, , vol. 19, p. 1633,1636
Org. Synth. Coll., , vol. Vol. IV, p. 166

63503-60-63-氯苯硼酸+

10177-29-44-氯烟酸

141764-18-3

参考文献

Budzik, Brian; Garzya, Vincenzo; Shi, Dongchuan; Walker, Graham; Lauchart, Yann; Lucas, Adam J.; Rivero, Ralph A.; Langmead, Christopher J.; Watson, Jeannette; Wu, Zining; Forbes, Ian T.; Jin, Jian
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 12 p. 3545 - 3549

64-17-5乙醇+

10177-29-44-氯烟酸

37831-62-24-氯烟酸乙酯盐酸盐

参考文献

Journal of Organic Chemistry, , vol. 60, # 2 p. 292 - 296

10177-29-44-氯烟酸+

75-03-6碘乙烷

37831-62-24-氯烟酸乙酯盐酸盐

参考文献

WO2005/42538 A1, ;

Page/Page column 16; 17 ;
WO 2005/042538 A1

10177-29-44-氯烟酸

37831-62-24-氯烟酸乙酯盐酸盐

参考文献

Journal of Medicinal Chemistry, , vol. 55, # 23 p. 10475 - 10489

10177-29-44-氯烟酸

7418-65-74-氨基吡啶-3-羧酸

参考文献

Radinov, Rumen; Haimova, Marietta; Simova, Ekaterina
Synthesis, 1986 , # 11 p. 886 - 891

67-56-1甲醇+

10177-29-44-氯烟酸

63592-85-8甲基 4-氯烟酸酯

参考文献

Bristol-Myers Squibb Company; Vrudhula, Vivekananda M.; Pan, Senliang; Rajamani, Ramkumar; Macor, John E.; Bronson, Joanne J.; Dzierba, Carolyn Diane; Nara, Susheel Jethanand; Karatholuvhu, Maheswaran Sivasamban
Patent: US2013/237555 A1, 2013 ;
Location in patent: Paragraph 0159 ;

10177-29-44-氯烟酸+

74-88-4甲基碘

63592-85-8甲基 4-氯烟酸酯

参考文献

Imbert, Thierry; Monse, Barbara; Koek, Wouter
Patent: US2005/80085 A1, 2005 ;
Location in patent: Page/Page column 8 ;

10177-29-44-氯烟酸+

18107-18-1三甲基硅烷化重氮甲烷

63592-85-8甲基 4-氯烟酸酯

参考文献

CONVERGENCE PHARMACEUTICALS LIMITED; NORTON, David; ANDREOTTI, Daniele; WARD, Simon E; PROFETA, Roberto; SPADA, Simone; PRICE, Helen Susanne
Patent: WO2012/98400 A1, 2012 ;
Location in patent: Page/Page column 28-29 ;
WO 2012/098400 A1

186581-53-3重氮甲烷+

10177-29-44-氯烟酸

63592-85-8甲基 4-氯烟酸酯

参考文献

Winn, Martin; De, Biswanath; Zydowsky, Thomas M.; Altenbach, Robert J.; Basha, Fatima Z.; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 18 p. 2676 - 2688