3-苯基-5,6-二氢-4H-吡咯并[1,2-b]吡唑合成路线 （共 37 条）
反应条件
1.1: 9-bora-bicyclo[3.3.1]nonane
1.2: 20 h / 20 °C
2.1: triethylamine
3.1: hydrogenchloride / water / Reflux
4.1: Aliquatreg; 336; sodium carbonate; bis(dibenzylideneacetone)-palladium(0); tri-cyclo-hexyl-phosphine / ethylene glycol dimethyl ether; water / 1 h / 130 °C / Microwave irradiation
View Scheme
参考文献
Ichikawa, Hayato; Watanabe, Ryo; Fujino, Yuiko; Usami, Yoshihide
Tetrahedron Letters, 2011 , vol. 52, # 34 p. 4448 - 4451
反应条件
1: triethylamine
2: hydrogenchloride / water / Reflux
3: Aliquatreg; 336; sodium carbonate; bis(dibenzylideneacetone)-palladium(0); tri-cyclo-hexyl-phosphine / ethylene glycol dimethyl ether; water / 1 h / 130 °C / Microwave irradiation
View Scheme
参考文献
Ichikawa, Hayato; Watanabe, Ryo; Fujino, Yuiko; Usami, Yoshihide
Tetrahedron Letters, 2011 , vol. 52, # 34 p. 4448 - 4451
反应条件
sodium methylate in methanol
Yield given;
参考文献
Takano, Seiichi; Imamura, Yoko; Ogasawara, Kunio
Heterocycles, 1982 , vol. 19, # 7 p. 1223 - 1225
反应条件
1: hydrazine hydrate / ethanol
2: 1.) n-BuLi
3: 1.) t-BuLi / 1.) THF, 0 deg C
4: 1.) BH3Me2S, 2.) H2O2, NaOH
5: pyridine
6: CH3ONa / methanol
View Scheme
参考文献
Takano, Seiichi; Imamura, Yoko; Ogasawara, Kunio
Heterocycles, 1982 , vol. 19, # 7 p. 1223 - 1225
反应条件
1: Heating
2: hydrazine hydrate / ethanol
3: 1.) n-BuLi
4: 1.) t-BuLi / 1.) THF, 0 deg C
5: 1.) BH3Me2S, 2.) H2O2, NaOH
6: pyridine
7: CH3ONa / methanol
View Scheme
参考文献
Takano, Seiichi; Imamura, Yoko; Ogasawara, Kunio
Heterocycles, 1982 , vol. 19, # 7 p. 1223 - 1225
反应条件
1: 1.) t-BuLi / 1.) THF, 0 deg C
2: 1.) BH3Me2S, 2.) H2O2, NaOH
3: pyridine
4: CH3ONa / methanol
View Scheme
参考文献
Takano, Seiichi; Imamura, Yoko; Ogasawara, Kunio
Heterocycles, 1982 , vol. 19, # 7 p. 1223 - 1225
反应条件
1: 1.) BH3Me2S, 2.) H2O2, NaOH
2: pyridine
3: CH3ONa / methanol
View Scheme
参考文献
Takano, Seiichi; Imamura, Yoko; Ogasawara, Kunio
Heterocycles, 1982 , vol. 19, # 7 p. 1223 - 1225
反应条件
1: 78 percent / MnO2 / CH2Cl2 / 50 h / Ambient temperature
2: 63 percent / CCl4, triphenylphosphine
3: 33 percent / 80percent aq. N2H4, DBU / ethanol / 12 h / Heating
View Scheme
参考文献
Guzman-Perez; Maldonado
Synthetic Communications, 1991 , vol. 21, # 15-16 p. 1667 - 1674
反应条件
1: 63 percent / CCl4, triphenylphosphine
2: 33 percent / 80percent aq. N2H4, DBU / ethanol / 12 h / Heating
View Scheme
参考文献
Guzman-Perez; Maldonado
Synthetic Communications, 1991 , vol. 21, # 15-16 p. 1667 - 1674
反应条件
1.1: triethylamine / dichloromethane / 0.5 h / -20 °C
2.1: 9-bora-bicyclo[3.3.1]nonane
2.2: 20 h / 20 °C
3.1: triethylamine
4.1: hydrogenchloride / water / Reflux
5.1: palladium diacetate; triphenylphosphine / ethylene glycol dimethyl ether; water / 24 h / Reflux
View Scheme
参考文献
Ichikawa, Hayato; Watanabe, Ryo; Fujino, Yuiko; Usami, Yoshihide
Tetrahedron Letters, 2011 , vol. 52, # 34 p. 4448 - 4451
