1: 68 percent / DEAD, PH3P / benzene 2: 68 percent / Ce(NH4)2(NO3)6 / H2O; acetonitrile 3: HOAc / tetrahydrofuran; H2O / 60 °C View Scheme

Multi-step reaction with 7 steps 1: 72.5 percent / 2 N aq. HCl / tetrahydrofuran / 24 h / Ambient temperature2: 74.6 percent / camphorsulfonic acid / toluene / 4.5 h / Ambient temperature3: 93 percent / imidazole, 4-(dimethylamino)pyridine / dimethylformamide / 14 h / Ambient temperature4: 96.7 percent / LiAlH4 / tetrahydrofuran; diethyl ether / 0.08 h / 0 °C5: 1.) DMSO, pyridine, CF3COOH, 2.) dicyclohexylcarbodiimide / 1.) benzene, RT, 15 min, 2.) benzene, RT, 6 h6: 1.) potassium bis(trimethylsilyl)amide / 1.) THF, 0 deg C, 20 min, 2.) THF, 20 min7: 81.2 percent / pyridine*(HF)x / tetrahydrofuran / 2 h / Ambient temperature  

Multi-step reaction with 4 steps 1: NaI / acetone3: 81 percent / KN(SiMe3)2 / tetrahydrofuran / 0 °C4: 98 percent / pyridine, (HF)x / tetrahydrofuran  

Multi-step reaction with 2 steps 1: 68 percent / DEAD, PH3P / benzene2: 68 percent / Ce(NH4)2(NO3)6 / H2O; acetonitrile