2-(2-氨基吡啶-3-基)乙酸合成路线 （共 11 条）
反应条件
hydrogenchloride Heating;
参考文献
Technische Universitaet Kaiserslautern
Patent: EP2199292 A1, 2010 ;
Location in patent: Page/Page column 10 ;
EP 2199292 A1
反应条件
hydrogenchloride in tetrahydrofuran; diethyl ether; water
参考文献
Schering Corporation
Patent: US5023265 A1, 1991 ;
反应条件
hydrogenchloride Reflux;
参考文献
Cheng, Xinlai; Merz, Karl-Heinz; Vatter, Sandra; Christ, Jochen; Woelfl, Stefan; Eisenbrand, Gerhard
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 1 p. 247 - 255
反应条件
ammonium hydroxide; copper(II) sulfate T=135°C;
参考文献
Okuda; Robison
Journal of the American Chemical Society, 1959 , vol. 81, p. 740,742
反应条件
1: Et3N / CH2Cl2 2: 1.) n-BuLi / 1.) THF 3: 3N HCl / Heating View Scheme
参考文献
Cheng, Xinlai; Merz, Karl-Heinz; Vatter, Sandra; Christ, Jochen; Woelfl, Stefan; Eisenbrand, Gerhard
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 1 p. 247 - 255
反应条件
1: H2O2; aqueous acetic acid 2: POCl3 3: concentrated aqueous NH3; CuSO4 / 135 °C View Scheme
参考文献
Okuda; Robison
Journal of the American Chemical Society, 1959 , vol. 81, p. 740,742
反应条件
1: POCl3 2: concentrated aqueous NH3; CuSO4 / 135 °C View Scheme
参考文献
Okuda; Robison
Journal of the American Chemical Society, 1959 , vol. 81, p. 740,742
反应条件
1: aqueous ethanol 2: H2O2; aqueous acetic acid 3: POCl3 4: concentrated aqueous NH3; CuSO4 / 135 °C View Scheme
参考文献
Okuda; Robison
Journal of the American Chemical Society, 1959 , vol. 81, p. 740,742
反应条件
1: 1.) n-BuLi / 1.) THF 2: 3N HCl / Heating View Scheme
参考文献
Cheng, Xinlai; Merz, Karl-Heinz; Vatter, Sandra; Christ, Jochen; Woelfl, Stefan; Eisenbrand, Gerhard
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 1 p. 247 - 255
参考文献
Okuda; Robison
Journal of the American Chemical Society, 1959 , vol. 81, p. 740,742
