2-(二氟甲基)苯甲酸甲酯合成路线 (共 2 条)
反应条件
diethylamino-sulfur trifluoride; methanol in dichloromethane T=20°C; Inert atmosphere;
参考文献
TFCHEM
Patent: WO2009/121939 A2, 2009 ;
Location in patent: Page/Page column 60-61 ;
WO 2009/121939 A2
反应条件
water; sodium hydroxide
0.5 h; Reflux;
参考文献
SIRTRIS PHARMACEUTICALS, INC.; CASAUBON, Rebecca, L.; NARAYAN, Radha; OALMANN, Christopher; VU, Chi, B.
Patent: WO2013/59587 A1, 2013 ;
Location in patent: Page/Page column 190; 191 ;