trichlorophosphate in acetonitrile T=20°C; 3 h; Reflux;

trichlorophosphate T=90°C; 1 h;

dichlorophenyl phosphine oxide; phosphorus pentachloride T=220°C; Chlorination; 0.333333 h;

1: Oxonereg; / methanol; water / 3 h / 50 °C 2: benzoyl chloride; potassium carbonate / dichloromethane; water / 3 h / 0 - 20 °C 3: trichlorophosphate / acetonitrile / 3 h / 20 °C / |Reflux View Scheme

1.1: toluene / 48 h / 20 °C / Inert atmosphere 2.1: tetrahydrofuran / 6 h / -10 - 20 °C / Inert atmosphere 2.2: 0.5 h / 20 °C / Inert atmosphere 3.1: water View Scheme

1.1: toluene / 48 h / 20 °C / Inert atmosphere 2.1: tetrahydrofuran / 6 h / -10 - 20 °C / Inert atmosphere 2.2: 0.5 h / 20 °C / Inert atmosphere 3.1: bis-triphenylphosphine-palladium(II) chloride; sodium acetate / tetrahydrofuran; N,N-dimethyl acetamide / 17 h / 130 °C / Inert atmosphere View Scheme

1.1: hydrogenchloride / dichloromethane; diethyl ether / 1 h / 5 - 20 °C 1.2: 5 h / |Reflux 2.1: palladium diacetate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; caesium carbonate / toluene / 1.5 h / 120 °C / |Inert atmosphere; |Microwave irradiation 3.1: bis-triphenylphosphine-palladium(II) chloride; sodium acetate / N,N-dimethyl acetamide / 1 h / 150 °C / |Inert atmosphere; |Microwave irradiation View Scheme