6,11-二氢-5H-吡啶并[2,3-b][1,5]苯并二氮杂烷-5-酮合成路线 （共 17 条）
反应条件
in 2-(2-methoxy-ethoxy)-ethanol T=150°C; 6 h;
参考文献
Guidi, Antonio; Dimoulas, Tula; Giannotti, Danilo; Harmat, Nicholas
Patent: US2008/275023 A1, 2008 ;
Location in patent: Page/Page column 6 ;
US 20080275023 A1
反应条件
in dichloromethane; cyclohexanol
参考文献
American Home Products Corporation
Patent: US5932745 A1, 1999 ;
参考文献
Hargrave, Karl D.; Proudfoot, John R.; Grozinger, Karl G.; Cullen, Ernest; Kapadia, Suresh R.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 7 p. 2231 - 2241
参考文献
Hargrave, Karl D.; Proudfoot, John R.; Grozinger, Karl G.; Cullen, Ernest; Kapadia, Suresh R.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 7 p. 2231 - 2241
参考文献
Journal of Medicinal Chemistry, , vol. 34, # 7 p. 2231 - 2241
反应条件
sodium hydroxide 1.) DMSO, 2.) DMSO; Multistep reaction;
参考文献
Hargrave, Karl D.; Proudfoot, John R.; Grozinger, Karl G.; Cullen, Ernest; Kapadia, Suresh R.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 7 p. 2231 - 2241
反应条件
sodium hydroxide in dimethyl sulfoxide
参考文献
Hargrave, Karl D.; Proudfoot, John R.; Grozinger, Karl G.; Cullen, Ernest; Kapadia, Suresh R.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 7 p. 2231 - 2241
参考文献
Hargrave, Karl D.; Proudfoot, John R.; Grozinger, Karl G.; Cullen, Ernest; Kapadia, Suresh R.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 7 p. 2231 - 2241
反应条件
sodium hydride; dimethyl sulfoxide 1.) DMF, 2.) DMF; Multistep reaction;
参考文献
Hargrave, Karl D.; Proudfoot, John R.; Grozinger, Karl G.; Cullen, Ernest; Kapadia, Suresh R.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 7 p. 2231 - 2241
参考文献
Hargrave, Karl D.; Proudfoot, John R.; Grozinger, Karl G.; Cullen, Ernest; Kapadia, Suresh R.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 7 p. 2231 - 2241
