1.1: 69.1 percent / aq. NaOH / methanol / 1.5 h / Heating 2.1: KH; t-BuLi / diethyl ether; hexane / 0.33 h / -78 °C 2.2: B(n-BuO)3 / diethyl ether; hexane / -78 - 20 °C 2.3: 88 percent / aq. H3PO4 / diethyl ether; hexane / 0 - 20 °C 3.1: Pd(PPh3)4 / toluene / 1 h / 20 °C 3.2: aq. Na2CO3 / toluene; ethanol / 8 h / 105 °C 3.3: 91 percent / HCl / diethyl ether / 20 °C 4.1: 85 percent / Ca(BH4)2 / ethanol / 2 h / 20 °C 5.1: 92 percent / MnO2 / CH2Cl2 / 2 h / 20 °C View Scheme

1: 60.5 percent / 40percent NaOH / methanol / 1.5 h / Heating 2: 96.3 percent / H2O; acetic acid / 48 h / Ambient temperature 3: 89.1 percent / dimethylformamide; H2O / 1 h / Heating View Scheme

1: 60.5 percent / 40percent NaOH / methanol / 1.5 h / Heating 2: 96.3 percent / H2O; acetic acid / 48 h / Ambient temperature View Scheme