2-甲基-1-[(4-甲基苯基)磺酰基]-1H-吡咯并[2,3-b]吡啶合成路线 （共 2 条）
反应条件
1: 1-tosyl-1H-pyrrolo[2,3-b]pyridine With n-butyllithium in tetrahydrofuran; hexane T=-70°C; 0.5 h; Cooling with acetone-dry iceInert atmosphere; 2: methyl iodide in tetrahydrofuran; hexane T=-70°C; 3 h; Inert atmosphere;
参考文献
sanofi-aventis
Patent: US2009/253679 A1, 2009 ;
Location in patent: Page/Page column 37 ;
反应条件
potassium hydroxide in methanol T=20°C; 10 h; Reflux;
参考文献
sanofi-aventis
Patent: US2009/253679 A1, 2009 ;
Location in patent: Page/Page column 37 ;
