4-(4-乙氧基-4-氧代丁酰胺)烟酸乙酯合成路线 (共 2 条)
反应条件
calcium carbonate in toluene 7 h; Heating;
参考文献
Stukenbrock, Hendrik; Mussmann, Rainer; Geese, Marcus; Ferandin, Yoan; Lozach, Olivier; Lemcke, Thomas; Kegel, Simone; Lomow, Alexander; Burk, Ulrike; Dohrmann, Cord; Meijer, Laurent; Austen, Matthias; Kunick, Conrad
Journal of Medicinal Chemistry, 2008 , vol. 51, # 7 p. 2196 - 2207
反应条件
potassium hydride in N,N-dimethyl-formamide; toluene T=70°C; Dieckmann reaction; 4 h;
参考文献
Stukenbrock, Hendrik; Mussmann, Rainer; Geese, Marcus; Ferandin, Yoan; Lozach, Olivier; Lemcke, Thomas; Kegel, Simone; Lomow, Alexander; Burk, Ulrike; Dohrmann, Cord; Meijer, Laurent; Austen, Matthias; Kunick, Conrad
Journal of Medicinal Chemistry, 2008 , vol. 51, # 7 p. 2196 - 2207