反应条件
1: 5-methyl-isoxazol-3-ylamine With sodium hydride in N,N-dimethyl-formamide
cooling;
2: carbonic acid diphenyl ester in N,N-dimethyl-formamide
T=20°C;
参考文献
De Lucca, George V.; Ui, Tae Kim; Vargo, Brian J.; Duncia, John V.; Santella III, Joseph B.; Gardner, Daniel S.; Zheng, Changsheng; Liauw, Ann; Wang, Zhang; Emmett, George; Wacker, Dean A.; Welch, Patricia K.; Covington, Maryanne; Stowell, Nicole C.; Wadman, Eric A.; Das, Anuk M.; Davies, Paul; Yeleswaram, Swamy; Graden, Danielle M.; Solomon, Kimberly A.; Newton, Robert C.; Trainor, George L.; Decicco, Carl P.; Ko, Soo S.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 6 p. 2194 - 2211
