7-氯咪唑并[1,2-a]吡啶-2-羧酸合成路线 （共 2 条）
反应条件
1: With water; lithium hydroxide hydrate in tetrahydrofuran T=20°C; 3 h; 2: With hydrogenchloride in tetrahydrofuran; water
参考文献
FENG, Yangbo; CHEN, Yen Ting; SESSIONS, Hampton; MISHRA, Jitendra K.; CHOWDHURY, Sarwat; YIN, Yan; LOGRASSO, Philip; LUO, Jun-Li; BANNISTER, Thomas; SCHROETER, Thomas
Patent: WO2011/50245 A1, 2011 ;
Location in patent: Page/Page column 109 ;
WO 2011/050245 A1
反应条件
1.1: ethylene glycol dimethyl ether; ethanol / 4 h / 20 °C / Reflux 2.1: water; lithium hydroxide hydrate / tetrahydrofuran; methanol / 60 °C 2.2: pH 4 View Scheme
参考文献
FENG, Yangbo; CHEN, Yen Ting; SESSIONS, Hampton; MISHRA, Jitendra K.; CHOWDHURY, Sarwat; YIN, Yan; LOGRASSO, Philip; LUO, Jun-Li; BANNISTER, Thomas; SCHROETER, Thomas
Patent: WO2011/50245 A1, 2011 ;
WO 2011/050245 A1
