in hexane; 1,2-dichloro-ethane T=20°C; 74 h; Yield given. Yields of byproduct given;

in hexane; toluene T=-40°C; Hydrogenation; 22 h; Title compound not separated from byproducts;

暂无反应条件数据

(i) Na, Et2O, (ii) /BRN= 635650/; Multistep reaction;

Irradiationwith and without benzophenone, different temperatures; Product distribution;

beim Kochen des Reaktionsprodukts mit alkoh. HCl;

1: 2 N aq. NaOH / ethanol 2: neat (no solvent) / 100 °C 3: 24.3 g / Br2, PCl3 / 1.) 80 - 85 deg C, 3 h, 2.) 100 deg C, 1 h View Scheme

formaldehyd in water

lithium aluminium tetrahydride in tetrahydrofuran 72 h; Reflux;

1.1: sodium hydroxide 2.1: diethylamine / ethyl acetate / Reflux 2.2: Reflux 3.1: sulfuric acid / 12 h / Reflux 4.1: lithium aluminium tetrahydride; AlCl3, aluminium chloride / diethyl ether / 2 h / -20 - 20 °C 5.1: triethylamine / dichloromethane / 3 h / 0 °C 6.1: sodium azide / dimethyl sulfoxide / 20 h / 70 °C / Inert atmosphere 7.1: triphenylphosphine / diethyl ether / 1 h / 0 °C 7.2: 20 h / 20 °C 8.1: potassium carbonate / dichloromethane / 4.42 h / 0 - 20 °C 9.1: 4-(N,N-dimethlyamino)pyridine / acetonitrile / 5 h 10.1: Grubb's 2nd generation catalyst / toluene / 15 h / 80 °C / Inert atmosphere 11.1: sodium tetrahydroborate; NiII chloride hexahydrate / methanol / 1.25 h / 15 °C 12.1: trifluoroacetic acid / dichloromethane / 0.75 h / 0 °C View Scheme