(9CI)-5,6-二氢-6,6-二甲基吡啶并[3,2-e]吡咯并[1,2-a]吡嗪合成路线 （共 6 条）
反应条件
sodium hydroxide T=30°C; 0.5 h;
参考文献
Lancelot, Jean-Charles; Rault, Sylvain; Laduree, Daniel; Robba, Max
Chemical & Pharmaceutical Bulletin, 1985 , vol. 33, # 7 p. 2798 - 2802
反应条件
hydrogenchloride; iron in water 48 h; Reflux;
参考文献
Organic Letters, , vol. 14, # 18 p. 4754 - 4757,4
反应条件
1: 47 percent / acetic acid / 2.5 h / Heating 2: 71 percent / hydrazine hydrate / Raney nickel / ethanol / 5 h / Heating 3: 86 percent / HCl gas / diethyl ether / 0.5 h 4: 62 percent / 2 h / Heating 5: 48 percent / 10 percent NaOH / 0.5 h / 30 °C View Scheme
参考文献
Lancelot, Jean-Charles; Rault, Sylvain; Laduree, Daniel; Robba, Max
Chemical & Pharmaceutical Bulletin, 1985 , vol. 33, # 7 p. 2798 - 2802
反应条件
1: 71 percent / hydrazine hydrate / Raney nickel / ethanol / 5 h / Heating 2: 86 percent / HCl gas / diethyl ether / 0.5 h 3: 62 percent / 2 h / Heating 4: 48 percent / 10 percent NaOH / 0.5 h / 30 °C View Scheme
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 33, # 7 p. 2798 - 2802
反应条件
1: 86 percent / HCl gas / diethyl ether / 0.5 h 2: 62 percent / 2 h / Heating 3: 48 percent / 10 percent NaOH / 0.5 h / 30 °C View Scheme
参考文献
Lancelot, Jean-Charles; Rault, Sylvain; Laduree, Daniel; Robba, Max
Chemical & Pharmaceutical Bulletin, 1985 , vol. 33, # 7 p. 2798 - 2802
反应条件
1: 62 percent / 2 h / Heating 2: 48 percent / 10 percent NaOH / 0.5 h / 30 °C View Scheme
参考文献
Lancelot, Jean-Charles; Rault, Sylvain; Laduree, Daniel; Robba, Max
Chemical & Pharmaceutical Bulletin, 1985 , vol. 33, # 7 p. 2798 - 2802
