4-氟-alpha-(2-甲基-1-氧代丙基)-gamma-氧代-beta-(苯基-2,3,4,5,6-d5)-N-[2-(苯基甲氧基)苯基]苯丁酰胺合成路线 (共 5 条)
反应条件
1: 76 percent / toluene / Heating 2: β-alanine; glacial acetic acid / hexane / Heating 3: 3-ethyl-5-(2-hydroxyethyl)-4-methylthiazolium bromide; triethylamine / ethanol / Heating View Scheme
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 43, # 3 p. 261 - 270
反应条件
1: 67 percent / sodium dithionite / methanol 2: 76 percent / toluene / Heating 3: β-alanine; glacial acetic acid / hexane / Heating 4: 3-ethyl-5-(2-hydroxyethyl)-4-methylthiazolium bromide; triethylamine / ethanol / Heating View Scheme
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 43, # 3 p. 261 - 270
反应条件
1: β-alanine; glacial acetic acid / hexane / Heating 2: 3-ethyl-5-(2-hydroxyethyl)-4-methylthiazolium bromide; triethylamine / ethanol / Heating View Scheme
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 43, # 3 p. 261 - 270
反应条件
3-ethyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazolium bromide; triethylamine in ethanol Addition; Heating;
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 43, # 3 p. 261 - 270
反应条件
1: pivalic acid / tetrahydrofuran; toluene; heptane / Heating 2: 81 percent / hydrogen; acetic acid / palladium on carbon / ethyl acetate View Scheme
参考文献
Chen, Bang-Chi; Sundeen, Joseph E.; Guo, Peng; Bednarz, Mark S.; Hangeland, Jon J.; Ahmed, Syed Z.; Jemal, Mohammed
Journal of Labelled Compounds and Radiopharmaceuticals, 2000 , vol. 43, # 3 p. 261 - 270