(3-溴苯基)(对甲苯)甲酮合成路线 (共 11 条)
反应条件
aluminium trichloride; toluene T=90°C;
参考文献
Ipatieff; Friedman
Journal of the American Chemical Society, 1939 , vol. 61, p. 684,688
反应条件
aluminium trichloride in chlorobenzene
参考文献
Nakatani, Kazuhiko; Dohno, Chikara; Saito, Isao
Journal of Organic Chemistry, 1999 , vol. 64, # 18 p. 6901 - 6904
反应条件
1: meta-dibromobenzene With n-butyllithium in tetrahydrofuran T=-78°C; 0.5 h; 2: 4-cyanotoluene in tetrahydrofuran T=-78°C;
参考文献
Caron, Stephane; Do, Nga M.
Synlett, 2004 , # 8 p. 1440 - 1442
反应条件
1: meta-dibromobenzene With iodine; magnesium in diethyl ether T=20 - 30°C; Inert atmosphere; 2: N-methoxy-N,4-dimethylbenzamide in diethyl ether T=0 - 20°C; Inert atmosphere;
参考文献
Kishore Kumar; Chavarria, Gustavo E.; Charlton-Sevcik, Amanda K.; Arispe, Wara M.; MacDonough, Matthew T.; Strecker, Tracy E.; Chen, Shen-En; Siim, Bronwyn G.; Chaplin, David J.; Trawick, Mary Lynn; Pinney, Kevin G.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 4 p. 1415 - 1419
反应条件
1: SOCl2 / 1 h / Heating 2: 5.75 g / AlCl3 / toluene / 3 h / 20 °C View Scheme
参考文献
Slootmaekers,P.J. et al.
Bulletin des Societes Chimiques Belges, 1966 , vol. 75, p. 199 - 229
反应条件
in various solvent(s) T=25°C; solvent: CF3SO3H; Rate constant;
参考文献
Roberts, R. M. G.; Sadri, A. R.
Tetrahedron, 1983 , vol. 39, # 1 p. 137 - 142
参考文献
Lapkin et al.
Sb. Statei Obshch. Khim., 1953 , p. 823,827
Chem.Abstr., 1955 , p. 6876
参考文献
de Roos; Rekker; Nauta
Arzneimittel-Forschung, 1971 , vol. 21, # 6 p. 818 - 820
反应条件
sodium tetrahydroborate in isopropyl alcohol
参考文献
Mindl,J.; Vecera,M.
Collection of Czechoslovak Chemical Communications, 1972 , vol. 37, p. 1143 - 1149
反应条件
1: 83 percent / NBS; AIBN / acetonitrile / 5 h / Heating 2: 81 percent / NaOAc / dimethylformamide / 8 h / Heating 3: 85 percent / sodium formate; NH2OH*HCl / formic acid / 3 h / Heating View Scheme
参考文献
Nakatani, Kazuhiko; Dohno, Chikara; Saito, Isao
Journal of Organic Chemistry, 1999 , vol. 64, # 18 p. 6901 - 6904