(20S)-3beta-乙酰氧基孕甾-5-烯-20-甲醛合成路线 （共 9 条）
反应条件
1: With oxygen; ozone in pyridine; dichloromethane 2: With zinc in pyridine; dichloromethane; acetic acid T=20°C; 4 h;
参考文献
Cui, JianGuo; Zeng, LongMei; Su, JingYu; Lu, WeiGang
Steroids, 2001 , vol. 66, # 1 p. 33 - 38
反应条件
pyridinium chlorochromate in dichloromethane T=20°C; Molecular sieveInert atmosphere;
参考文献
Gigante, Federica; Kaiser, Marcel; Brun, Reto; Gilbert, Ian H.
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 16 p. 5950 - 5961
反应条件
1: 98 percent / BH3*DMS / tetrahydrofuran / 20 °C 2: 75 percent / pyridinium chlorochromate; 3 Angstroem molecular sieves / CH2Cl2 / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 20 p. 6094 - 6103
反应条件
1.1: 97 percent / Br2; idobenzene / hexane / -5 °C 2.1: ozone-rich oxygen / CH2Cl2; pyridine 2.2: 82 percent / Zn dust / acetic acid; CH2Cl2; pyridine / 4 h / 20 °C View Scheme
参考文献
Steroids, , vol. 66, # 1 p. 33 - 38
反应条件
quinoline; Pd-BaSO4; xylene Hydrogenation.Reagens 4:Schwefel;
参考文献
Journal of the American Chemical Society, , vol. 69, p. 1957,1959
反应条件
1.1: 96 percent / pyridine / 30 h / 20 °C 2.1: 97 percent / Br2; idobenzene / hexane / -5 °C 3.1: ozone-rich oxygen / CH2Cl2; pyridine 3.2: 82 percent / Zn dust / acetic acid; CH2Cl2; pyridine / 4 h / 20 °C View Scheme
参考文献
Steroids, , vol. 66, # 1 p. 33 - 38
反应条件
gallium(III) bromide in diethyl ether T=-17°C; 3 h; Yields of byproduct given;
参考文献
Sucrow, Wolfgang; Nooy, Michael van
Liebigs Annalen der Chemie, 1982 , # 10 p. 1897 - 1906
反应条件
(i) O3, CH2Cl2, (ii) Zn, AcOH; Multistep reaction;
参考文献
Chemische Berichte, , vol. 99, p. 2765 - 2777
反应条件
1: (i) EtMgBr, Et2O, THF, (ii) /BRN= 2480416/, benzene 2: H2 / Lindlar catalyst / ethyl acetate 3: toluene 4: LiAlH4 / diethyl ether 5: (i) aq. H2O2, MeOH, (ii) DMSO View Scheme
参考文献
Sucrow,W. et al.
Chemische Berichte, 1973 , vol. 106, p. 2236 - 2245
