4-[(5,6,7,8-四氢-5,5,8,8-四甲基-2-萘基)甲酰氨基]苯甲酸合成路线 （共 3 条）
反应条件
1: With methanol; potassium hydroxide 16 h; Heating / reflux; 2: With hydrogenchloride in water; ethyl acetate
参考文献
EP1541549 A1, ;
Page/Page column 13-14; 37 ;
反应条件
1: 1.) SOCl2, 2.) 4-(dimethylamino)pyridine / 1.) 0 deg C, 30 min, 2.) pyridine, 60 deg C, 2 h 2: 77.2 percent / aq. NaOH / ethanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 31, # 11 p. 2182 - 2192
反应条件
1: 1.) SOCl2, 2.) 4-(dimethylamino)pyridine / 1.) 0 deg C, 30 min, 2.) pyridine, 60 deg C, 2 h 2: 77.2 percent / aq. NaOH / ethanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 31, # 11 p. 2182 - 2192
