(3S)-3-(叔丁氧羰基)氨基-1-氯-4-苯基-2-丁酮合成路线 （共 24 条）
反应条件
hydrogenchloride in toluene
参考文献
Kaneka Corporation
Patent: US6150567 A1, 2000 ;
反应条件
methanesulfonic acid in hexane; toluene
参考文献
Kaneka Corporation
Patent: US6255522 B1, 2001 ;
参考文献
Kaneka Corporation
Patent: US6150567 A1, 2000 ;
参考文献
Kaneka Corporation
Patent: US6150567 A1, 2000 ;
反应条件
potassium phosphate buffer; Streptomyces nodosus SC 13149 T=28°C; microbial reduction; pH=6.8; 48 h;
参考文献
Patel, Ramesh N.
JAOCS, Journal of the American Oil Chemists' Society, 1999 , vol. 76, # 11 p. 1275 - 1281
反应条件
1: aluminum isopropoxide / isopropyl alcohol / 3 h / |Reflux 2: sodium carbonate / water / 3 h / 60 - 65 °C View Scheme
参考文献
MYLAN LABORATORIES LTD; VELLANKI, Siva Rama Prasad; SAHU, Arabinda; PHADHURI, Naveen Kumar; KILARU, Ravindrababu
Patent: WO2013/114382 A1, 2013 ;
反应条件
sodium tetrahydroborate in tetrahydrofuran; water T=0°C; 0.75 h;
参考文献
Barrish, Joel C.; Gordon, Eric; Alam, Masud; Lin, Pin-Fang; Bisacchi, Gregory S.; et al.
Journal of Medicinal Chemistry, 1994 , vol. 37, # 12 p. 1758 - 1768
反应条件
Rhodococcus erythropolis SC 13845 in phosphate buffer pH=7.0; 49 h; Microbiological reaction;
参考文献
Patel, Ramesh N.; Chu, Linda; Mueller, Richard
Tetrahedron Asymmetry, 2003 , vol. 14, # 20 p. 3105 - 3109
反应条件
anhydrous potassium hydrogen sulfate in diethyl ether; ethyl acetate
参考文献
Ajinomoto Co., Inc.
Patent: US2002/72621 A1, 2002 ;
反应条件
hydrogenchloride in diethyl ether
参考文献
AJINOMOTO CO. INC
Patent: US2002/151722 A1, 2002 ;
