3-溴-7-氯-6-碘-1H-喹啉-4-酮合成路线 （共 2 条）
反应条件
N-bromosuccinmide in acetic acid T=60°C; 2 h;
参考文献
Wolkenberg, Scott E.; Zhao, Zhijian; Thut, Catherine; Maxwell, Jill W.; McDonald, Terrence P.; Kinose, Fumi; Reilly, Michael; Lindsley, Craig W.; Hartman, George D.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 7 p. 2351 - 2358
反应条件
1: 1 h / 120 °C 2: diphenylether / 1 h / 250 °C 3: sodium hydroxide / water / Reflux 4: diphenylether / 1 h / 250 °C 5: N-bromosuccinmide; acetic acid / 2 h / 60 °C View Scheme
参考文献
Wolkenberg, Scott E.; Zhao, Zhijian; Thut, Catherine; Maxwell, Jill W.; McDonald, Terrence P.; Kinose, Fumi; Reilly, Michael; Lindsley, Craig W.; Hartman, George D.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 7 p. 2351 - 2358
