2-苯基-4-[3H]喹唑啉酮合成路线 (共 178 条)
反应条件
1: potassium carbonate / dimethyl sulfoxide / 4 h / 90 °C 2: 2 h / 90 °C 3: water / 1 h / 20 °C View Scheme
参考文献
Journal of Chemical Research, , vol. 36, # 12 p. 701 - 702
反应条件
1: potassium carbonate / dimethyl sulfoxide / 4 h / 90 °C 2: 2 h / 90 °C 3: water / 1 h / 20 °C View Scheme
参考文献
Journal of Chemical Research, , vol. 36, # 12 p. 701 - 702
反应条件
1: triethylamine; ammonia / tetrahydrofuran; water / 2.5 h 2: toluene-4-sulfonic acid / tetrahydrofuran / 0.17 h / 20 °C 3: [bis(acetoxy)iodo]benzene / tetrahydrofuran / 1 h / 20 °C View Scheme
参考文献
Synthesis (Germany), , vol. 45, # 21 art. no. SS-2013-H0422-OP, p. 2998 - 3006
反应条件
phosphorus pentoxide; xylene T=175 - 190°C;
参考文献
Journal of the Indian Chemical Society, , vol. 6, p. 282
Chem. Zentralbl., , vol. 100, # II p. 887
反应条件
in paraffin T=300°C;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 633 - 638
反应条件
sodium ethanolate in ethanol 2 h; Heating;
参考文献
Gazzetta Chimica Italiana, , vol. 117, # 7 p. 385 - 390
反应条件
1.1: sodium hydride / dimethyl sulfoxide; mineral oil / 0 - 20 °C / Inert atmosphere 1.2: Inert atmosphere; Cooling with ice 2.1: palladium diacetate; acetic acid; copper(II) oxide / 4 h / 110 °C / 760.05 Torr View Scheme
参考文献
Journal of Organic Chemistry, , vol. 76, # 15 p. 6362 - 6366
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium acetate in ethanol; water; toluene Reflux;
参考文献
Investigational New Drugs, , vol. 30, # 5 p. 2035 - 2045
反应条件
1: palladium diacetate; 1,8-diazabicyclo[5.4.0]undec-7-ene; di-(1-adamantyl)-n-butylphosphine / N,N-dimethyl-formamide / 16 h / 130 °C / |Inert atmosphere; |Sealed tube 2: urea hydrogen peroxide addition compound / N,N-dimethyl-formamide / 7 h / 100 °C View Scheme
参考文献
Tetrahedron, , vol. 70, # 1 p. 23 - 29
反应条件
1: 60 percent / nitromethane / 12 h / 60 - 70 °C 2: 55 percent / dimethylformamide / 8 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 42, # 5 p. 1449 - 1460