2-苯基-4-[3H]喹唑啉酮合成路线 （共 178 条）
反应条件
1: [bis(acetoxy)iodo]benzene; palladium diacetate / 1,2-dichloro-ethane / 8 h / Reflux 2: ammonia; lithium / tetrahydrofuran / 0.33 h / -78 °C View Scheme
参考文献
Reddy, B.V. Subba; Narasimhulu; Umadevi; Yadav
Synlett, 2012 , vol. 23, # 9 p. 1364 - 1370
反应条件
1: potassium carbonate / tetrahydrofuran / 0.5 h / 60 °C / |Inert atmosphere 2: bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran; water / |Inert atmosphere View Scheme
参考文献
Qiu, Guanyinsheng; Huang, Ping; Yang, Qin; Lu, Hui; Xu, Jingshi; Deng, Zhihong; Zhang, Ming; Peng, Yiyuan
Synthesis (Germany), 2013 , vol. 45, # 22 art. no. SS-2013-H0390-OP, p. 3131 - 3136
反应条件
1.1: trichlorophosphate / 2 h / Reflux
2.1: phenol / 2 h / 170 °C
2.2: 1 h / 150 °C
View Scheme
参考文献
Marvania, Bhavin; Lee, Pei-Chih; Chaniyara, Ravi; Dong, Huajin; Suman, Sharda; Kakadiya, Rajesh; Chou, Ting-Chao; Lee, Te-Chang; Shah, Anamik; Su, Tsann-Long
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 6 p. 1987 - 1998
反应条件
1: [bis(acetoxy)iodo]benzene; palladium diacetate / 1,2-dichloro-ethane / 8 h / Reflux
2: ammonia; lithium / tetrahydrofuran / 0.33 h / -78 °C
View Scheme
参考文献
Reddy, B.V. Subba; Narasimhulu; Umadevi; Yadav
Synlett, 2012 , vol. 23, # 9 p. 1364 - 1370
反应条件
1: Lawesson's reagent / toluene / |Reflux
2: hydrazine hydrate / methanol / 12 h / |Reflux
3: 6 h / 120 °C
View Scheme
参考文献
Zheng, Yan; Bian, Ming; Deng, Xian-Qing; Wang, Shi-Ben; Quan, Zhe-Shan
Archiv der Pharmazie, 2013 , vol. 346, # 2 p. 119 - 126
反应条件
HBEA zeolite supported Pt metal nanocluster in 1,3,5-trimethyl-benzene
24 h; RefluxInert atmosphere;
参考文献
Hakim Siddiki; Kon, Kenichi; Touchy, Abeda Sultana; Shimizu, Ken-Ichi
Catalysis Science and Technology, 2014 , vol. 4, # 6 p. 1716 - 1719
反应条件
1: 2-phenyl-4(3H)-quinazolinone With oxygen; trichlorophosphate in dimethyl sulfoxide; N,N-dimethyl-formamide
T=50°C;
2: aniline in dimethyl sulfoxide; N,N-dimethyl-formamide
T=50°C;
参考文献
Kim, Na Yeun; Cheon, Cheol-Hong
Tetrahedron Letters, 2014 , vol. 55, # 15 p. 2340 - 2344
反应条件
1: thionyl chloride / 1,2-dichloro-ethane; N,N-dimethyl-formamide / 0.5 h / 50 °C
2: N,N-dimethyl-formamide / 2 h / 50 °C
View Scheme
参考文献
Juvale, Kapil; Gallus, Jennifer; Wiese, Michael
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 24 p. 7858 - 7873
