2-氨基-3-硝基-6-苯基吡啶合成路线 （共 8 条）
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; water; toluene T=90°C; 12 h;
参考文献
Takeda Chemical Industries, Ltd.
Patent: EP1460067 A1, 2004 ;
Location in patent: Page 43 ;
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in ethylene glycol dimethyl ether; ethanol; water T=100°C; 0.5 h; Inert atmosphereMicrowave irradiation;
参考文献
van Duzer, John H.; Mazitschek, Ralph
Patent: US2014/128391 A1, 2014 ;
Location in patent: Paragraph 0217; 0218; 0219 ;
反应条件
acetic acid in ethanol 4 h; Heating;
参考文献
Mertens, Hubert; Troschuetz, Reinhard; Roth, Hermann J.
Liebigs Annalen der Chemie, 1986 , # 2 p. 380 - 383
反应条件
ammonium acetate in ethanol 6 h; Heating;
参考文献
Mertens, Hubert; Troschuetz, Reinhard; Roth, Hermann J.
Liebigs Annalen der Chemie, 1986 , # 2 p. 380 - 383
反应条件
hydrogenchloride in ethanol 16 h; Heating;
参考文献
Batt; Houghton
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 3 p. 963 - 969
反应条件
acetic acid in ethanol Heating;
参考文献
Troschutz; Karger
Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 6 p. 1815 - 1821
反应条件
1: With hydrogenchloride; iron in methanol; water T=20 - 80°C; 1 h; 2: With sodium hydroxide in methanol; water T=0°C;
参考文献
Takeda Chemical Industries, Ltd.
Patent: EP1460067 A1, 2004 ;
Location in patent: Page 43 ;
反应条件
hydrogenchloride; sodium nitrite Ambient temperature;
参考文献
Troschuetz, Reinhard; Karger, Alexander
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 4 p. 1147 - 1151
