4-苯基-3-丁炔-1-醇合成路线 （共 39 条）
反应条件
sodium carbonate in water
T=25°C; 24 h; Further byproducts given;
参考文献
Collins, Clair J.; Hanack, Michael; Stutz, Herbert; Auchter, Gerhard; Schoberth, Winfried
Journal of Organic Chemistry, 1983 , vol. 48, # 26 p. 5260 - 5268
反应条件
sodium carbonate in water
T=25°C; 24 h; Further byproducts given;
参考文献
Collins, Clair J.; Hanack, Michael; Stutz, Herbert; Auchter, Gerhard; Schoberth, Winfried
Journal of Organic Chemistry, 1983 , vol. 48, # 26 p. 5260 - 5268
反应条件
1: (i) MeLi, iPr2NH, (ii) /BRN= 2407037/
2: aq. EtOH, Et3N
View Scheme
参考文献
Hanack,M. et al.
Journal of the American Chemical Society, 1979 , vol. 101, p. 100 - 108
反应条件
indium in water
Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Isaac, Methvin B.; Chan, Tak-Hang
Journal of the Chemical Society, Chemical Communications, 1995 , # 10 p. 1003 - 1004
参考文献
Faucounau
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1934 , vol. 199, p. 605
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Golse
Annales de Chimie (Cachan, France), 1948 , vol. <12> 3, p. 527,554
反应条件
triethylamine in ethanol; water
T=25°C; 24 h; var. 4-subst.-homopropargyl esters (tosylates and triflates), var. solvents, buffers, temp.s and times; Product distributionMechanism;
参考文献
Collins, Clair J.; Hanack, Michael; Stutz, Herbert; Auchter, Gerhard; Schoberth, Winfried
Journal of Organic Chemistry, 1983 , vol. 48, # 26 p. 5260 - 5268
反应条件
1: CrO3; aqueous H2SO4
2: zinc carbonate
View Scheme
参考文献
Schulte et al.
Archiv der Pharmazie (Weinheim, Germany), 1958 , vol. 291, p. 227,236
反应条件
in N,N,N',N',N'',N''-hexamethylphosphoric triamide
T=250°C;
参考文献
Collins, Clair J.; Hanack, Michael; Stutz, Herbert; Auchter, Gerhard; Schoberth, Winfried
Journal of Organic Chemistry, 1983 , vol. 48, # 26 p. 5260 - 5268
反应条件
1: pyridine / or Li-salt of the corresponding acetylenic alcohol
2: NaN3 / dimethylformamide / 4 h / 60 - 70 °C
3: LiAlH4 / diethyl ether / 0 °C
4: 63 percent / PdCl2(MeCN)2 / acetonitrile; H2O / 5 h / Heating
View Scheme
参考文献
Fukuda, Yukitoshi; Matsubara, Seijiro; Utimoto, Kiitiro
Journal of Organic Chemistry, 1991 , vol. 56, # 20 p. 5812 - 5816
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine
Inert atmosphere;
参考文献
Fang, Fang; Vogel, Megan; Hines, Jennifer V.; Bergmeier, Stephen C.
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 15 p. 3080 - 3091
