4-溴-2-苯并呋喃-1(3H)-酮合成路线 （共 14 条）
反应条件
chromium oxychloride in tetrachloromethane 20 h; Heating;
参考文献
Xiao, Xiangshu; Antony, Smitha; Pommier, Yves; Cushman, Mark
Journal of Medicinal Chemistry, 2006 , vol. 49, # 4 p. 1408 - 1412
反应条件
1: With hydrogen bromide; sodium nitrite in water T=5°C; 2: With hydrogen bromide; copper(I) bromide in water T=70 - 75°C; Sandmeyer reaction; 2 h;
参考文献
Wang, Wei; Cha, Xue-Xiang; Reiner, John; Gao, Yuan; Qiao, Hai-Ling; Shen, Jia-Xiang; Chang, Jun-Biao
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 5 p. 1941 - 1946
参考文献
Canadian Journal of Chemistry, , vol. 65, p. 1214 - 1217
反应条件
chromium oxychloride in tetrachloromethane T=0°C; 23 h; Reflux;
参考文献
Zhang, Peng; Cyriac, George; Kopajtic, Theresa; Zhao, Yongfang; Javitch, Jonathan A.; Katz, Jonathan L.; Newman, Amy Hauck
Journal of Medicinal Chemistry, 2010 , vol. 53, # 16 p. 6112 - 6121
反应条件
lithium borohydride in tetrahydrofuran Yields of byproduct given;
参考文献
Soucy, C.; Favreau, D.; Kayser, M. M.
Journal of Organic Chemistry, 1987 , vol. 52, # 1 p. 129 - 134
反应条件
1: 94 percent / H2SO4 / 12 h / 20 °C / Heating 2: 75 percent / chromyl chloride / CCl4 / 20 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 4 p. 1408 - 1412
反应条件
1: 60 percent / Br2, triphenylphosphine / acetonitrile 2: 37 percent / cetyltrimethylammonium bromide, KMnO4 / H2O / 24 h / 50 - 60 °C 3: 88 percent / acetic anhydride / 1 h / Heating 4: diisobutylaluminum hydride (DIBAL-H) / tetrahydrofuran / 2 h / -78 - -60 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 52, # 1 p. 129 - 134
反应条件
1: 37 percent / cetyltrimethylammonium bromide, KMnO4 / H2O / 24 h / 50 - 60 °C 2: 88 percent / acetic anhydride / 1 h / Heating 3: diisobutylaluminum hydride (DIBAL-H) / tetrahydrofuran / 2 h / -78 - -60 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 52, # 1 p. 129 - 134
反应条件
1: 88 percent / acetic anhydride / 1 h / Heating 2: diisobutylaluminum hydride (DIBAL-H) / tetrahydrofuran / 2 h / -78 - -60 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 52, # 1 p. 129 - 134
反应条件
1: sulfuric acid; potassium nitrate 2: tin (II)-chloride; aqueous hydrochloric acid / Behandeln des Reaktionsprodukts mit wss. Natronlauge 3: ueber die Diazonium-Verbindung View Scheme
参考文献
Bulletin de la Societe Scientifique de Bretagne, , vol. 26, p. Sonderheft 5, S. 7, 96
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 235, p. 962
